CARTILAGE

作品数:334被引量:864H指数:13
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相关领域:医药卫生更多>>
相关作者:乔洋陶虹月陈爽侯树勋彭宝淦更多>>
相关机构:湘雅医院复旦大学中国人民解放军总医院华中科技大学更多>>
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相关基金:国家自然科学基金中国博士后科学基金高等学校学科创新引智计划国家高技术研究发展计划更多>>
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Sturgeon cartilage-derived chondroitin sulfate exhibited anti-inflammatory activity against dextran sulfate sodium-induced colitis via modification of gut microbiota
《Food Science and Human Wellness》2025年第4期1239-1250,共12页Ruiyun Wu Zixin Han Zhenyu Wang Pinglan Li Nan Shang 
funded by grants from Beijing Fishery Innovation Team Project(BAIC07-2023-13);National Natural Science Foundation of China(32201994)。
Chondroitin sulfate(CS)is one of the main bioactive compounds in animal cartilage.In this study,the antiinflammatory activity of sturgeon-derived chondroitin sulfate(SCS)was evaluated in the dextran sulfate sodium(DSS...
关键词:Sturgeon cartilage Chondroitin sulfate Anti-inflammatory activity Dextran sulfate sodium-induced colitis Gut microbiota 
Diced cartilage in capsula based on diced cartilage in fascia technique:A case report
《World Journal of Clinical Cases》2025年第19期92-98,共7页Henri Stephan Hady Rihani Elie Dagher Jad El Choueiri 
BACKGROUND The Turkish Delight technique,initially described by Erol in 2000,involves the use of diced cartilage wrapped in oxidized cellulose(Surgicel^(TM))for nasal grafting in secondary rhinoplasty.CASE SUMMARY Thi...
关键词:Diced Cartilage in Capsula Diced Cartilage in Fascia Turkish delight Periprosthetic capsule RHINOPLASTY Case report 
Effect of older age and/or ACL injury on the dose-response relationship between ambulatory load magnitude and immediate load-induced change in serum cartilage oligomeric matrix protein
《Journal of Sport and Health Science》2025年第2期54-64,共11页Simon Herger Corina Nüesch Anna-Maria Liphardt Christian Egloff Annegret Mündermann 
funded by the Swiss National Science Foundation(#184912,in 2019);funding from the German Research Foundation(SFB 1483,in 2021).
Purpose:This study aimed to assess the influence of older vs.younger age and previous anterior cruciate ligament(ACL)injury on resting serum cartilage oligomeric matrix protein(sCOMP(t_(pre)))concentration,on immediat...
关键词:Aging Cartilage blood biomarker Knee injury MECHANOSENSITIVITY Risk for OA 
Single-cell transcriptomic analysis of chondrocytes in cartilage and pathogenesis of osteoarthritis
《Genes & Diseases》2025年第2期383-397,共15页Changyuan Huangg Bin Zeng Bo Zhou Guanming Chen Qi Zhang Wenhong Hou Guozhi Xiao Li Duan Ni Hong Wenfei Jin 
supported by the National Key R&D Program of China (No.2021YFF1200900);National Natural Science Foundation of China (No.32170646,8197211);Guangdong Basic and Applied Basic Research Foundation (China) (No.2023A1515011908 to N.H.);Key-Area Research and Development Program of Guangdong Province,China (No.2023B1111020006);International Science and Technology CooperationnProgramnofGuangdong,China (No.2021A0505030011);Shenzhen Innovation Committee of Science and Technology (Guangdong,China) (No.JCYJ20220818100401003);Shenzhen Science and Technology Program (Guangdong,China) (No.SGDX20201103095800003,GJHZ20200731095606019,JCYJ20220818100401003);Shenzhen High-level Hospital Construction Fund (Guangdong,China) (No.1801004).
Chondrocyte is considered the only cell type in cartilage.However,the cell hetero-geneity of chondrocytes in human articular cartilage is still not well defined,which hinders our understanding of the pathogenesis of o...
关键词:Cell heterogeneity Chondrocyte apoptosis Chondrocyte differentiation Chondrocyte fibrosis OSTEOARTHRITIS Single-cell RNA-seq 
Signaling pathway mechanisms of circadian clock gene Bmal1regulating bone and cartilage metabolism:a review
《Bone Research》2025年第1期35-47,共13页Yiting Ze Yongyao Wu Zhen Tan Rui Li Rong Li Wenzhen Gao Qing Zhao 
National Natural Science Foundation of China(82171003 and 82171002);Research and Develop Program of West China Hospital of Stomatology Sichuan University(NO.LCYJ-2022-YY-1)。
Circadian rhythm is ubiquitous in nature.Circadian clock genes such as Bmal1 and Clock form a multi-level transcription-translation feedback network,and regulate a variety of physiological and pathological processes,i...
关键词:BMAL1 METABOLISM CARTILAGE 
Neuronal guidance factor Sema3A inhibits neurite ingrowth and prevents chondrocyte hypertrophy in the degeneration of knee cartilage in mice,monkeys and humans
《Bone Research》2025年第1期75-90,共16页Shishu Huang Dashuang Gao Zhenxia Li Hongchen He Xi Yu Xuanhe You Diwei Wu Ze Du Jiancheng Zeng Xiaojun Shi Qinshen Hu Yong Nie Zhong Zhang Zeyu Luo Duan Wang Zhihe Zhao Lingli Li Guanglin Wang Liping Wang Zongke Zhou Di Chen Fan Yang 
partly National Key R&D Program of China(2023YFA1801200,2023YFA1801202);Major Program of the National Natural Science Foundation of China(T2394532);National Natural Science Foundation of China(82072489);The Foundation of Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions(NYKFKT2019007);Shenzhen Medical Research Fund(B2302011);The Sanming Project of Medicine in Shenzhen(SZZYSM202311013);The China Postdoctoral Science Foundational,2023M743679;Shenzhen Science and Technology Research Funding(JCYJ20220818101414032);Key Research Project of Science&Technology Department of Sichuan Province,China(2024YFFK0041)。
Osteoarthritis(OA)is a degenerative joint disease accompanied with the loss of cartilage and consequent nociceptive symptoms.Normal articular cartilage maintains at aneural state.Neuron guidance factor Semaphorin 3A(S...
关键词:SEMA3A CARTILAGE HYPERTROPHY 
Wnt2bb signaling promotes pharyngeal chondrogenic precursor proliferation and chondrocyte maturation by activating Yap expression in zebrafish
《Journal of Genetics and Genomics》2025年第2期220-230,共11页Xiaojuan Guo Liping Yang Yujie Wang Mengna Yuan Wenqing Zhang Xinyu He Qiang Wang 
support of the National Natural Science Foundation of China(32025014 and 32330029 to Q.W.);the National Key Research and Development Program of China(2020YFA0804000 to Q.W.);Guangdong Excellent Youth Team Project(2024B1515040019 to Q.W.);Guangzhou Science and Technology Plan Project(202201010323 to X.H.);the Fundamental Research Funds for the Central Universities(to Q.W.).
Pharyngeal cartilage morphogenesis is crucial for the formation of craniofacial structures.Cranial neural crest cells are specified at the neural plate border,migrate to pharyngeal arches,and differentiate into pharyn...
关键词:Wnt/β-catenin signaling YAP Wnt2bb Chondrocyte maturation Pharyngeal cartilage ZEBRAFISH 
Nasal Tip-Columella Subunits Infrastructural Reconstruction: 10th Rib Cartilage Graft Operative Technique
《International Journal of Otolaryngology and Head & Neck Surgery》2025年第1期47-56,共10页Wenbo Huang Takkun Chow Sikkuen Chow Yangliu Liao 
Background: Reconstruction of Nasal Tip Columella (NTC) subunits is one of the most challenging aspects in functional aesthetic rhinoplasty. Moreover, racial variation for Asian nose rhinoplasty could even demand soph...
关键词:Nasal Tip Columella Rhinoplasty 10th Rib Cartilage CLEFT Chinese 
Injectable cartilage microtissues based on 3D cultureusing porous gelatin microcarriers for cartilagedefect treatment
《Regenerative Biomaterials》2025年第1期72-83,共12页Jing Zhu Qiuchen Luo Tiefeng Cao Guang Yang Lin Xiao 
supported by the National Natural Science Foundation of China(52173151,82002734,51803067);the Natural Science Foundation of Guangdong Province of China(2021A1515011084,2019A1515110312);the Fundamental Research Funds for the Central Universities(22qntd1302);the Shenzhen Outbound Postdoctoral Scientific Research Fund(SZBH202108).
Cartilage tissues possess an extremely limited capacity for self-repair,and current clinical surgical approaches for treating articular cartilage defects can only provide short-term relief. Despite significantadvances...
关键词:cartilage repair microtissue engineering MICROCARRIERS GELATIN BMSCS 
3D bioprinted advanced cartilage organoids with engineered magnetic nanoparticles polarized-BMSCs/alginate/gelatin for cartilage tissue regeneration
《Nano Research》2025年第2期541-556,共16页Zhiyu Ding Junjie Huang Yijun Ren Ning Tang Xin Luo Huancheng Zhu Xu Cao Ming Zhao Song Wu 
This work was financially supported by Science and Technology Innovation Leading Plan of High-Tech Industry in Hunan Province(No.2020SK2011);The National Natural Science Foundation of China-Youth Science Fund(No.82204538);Macao Special Administrative Region Science and Technology Development Fund(No.0007/2021/AKP).
Cartilage defects are commonly observed in orthopedic clinical studies.Owing to the unique structure of cartilage tissue,current clinical treatments cannot fully address this issue.Cartilage organoids are three-dimens...
关键词:magnetic nanoparticles cell polarization three-dimensional(3D)bioprinting cartilage organoid cartilage repair 
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