funded by grants from Beijing Fishery Innovation Team Project(BAIC07-2023-13);National Natural Science Foundation of China(32201994)。
Chondroitin sulfate(CS)is one of the main bioactive compounds in animal cartilage.In this study,the antiinflammatory activity of sturgeon-derived chondroitin sulfate(SCS)was evaluated in the dextran sulfate sodium(DSS...
BACKGROUND The Turkish Delight technique,initially described by Erol in 2000,involves the use of diced cartilage wrapped in oxidized cellulose(Surgicel^(TM))for nasal grafting in secondary rhinoplasty.CASE SUMMARY Thi...
funded by the Swiss National Science Foundation(#184912,in 2019);funding from the German Research Foundation(SFB 1483,in 2021).
Purpose:This study aimed to assess the influence of older vs.younger age and previous anterior cruciate ligament(ACL)injury on resting serum cartilage oligomeric matrix protein(sCOMP(t_(pre)))concentration,on immediat...
supported by the National Key R&D Program of China (No.2021YFF1200900);National Natural Science Foundation of China (No.32170646,8197211);Guangdong Basic and Applied Basic Research Foundation (China) (No.2023A1515011908 to N.H.);Key-Area Research and Development Program of Guangdong Province,China (No.2023B1111020006);International Science and Technology CooperationnProgramnofGuangdong,China (No.2021A0505030011);Shenzhen Innovation Committee of Science and Technology (Guangdong,China) (No.JCYJ20220818100401003);Shenzhen Science and Technology Program (Guangdong,China) (No.SGDX20201103095800003,GJHZ20200731095606019,JCYJ20220818100401003);Shenzhen High-level Hospital Construction Fund (Guangdong,China) (No.1801004).
Chondrocyte is considered the only cell type in cartilage.However,the cell hetero-geneity of chondrocytes in human articular cartilage is still not well defined,which hinders our understanding of the pathogenesis of o...
National Natural Science Foundation of China(82171003 and 82171002);Research and Develop Program of West China Hospital of Stomatology Sichuan University(NO.LCYJ-2022-YY-1)。
Circadian rhythm is ubiquitous in nature.Circadian clock genes such as Bmal1 and Clock form a multi-level transcription-translation feedback network,and regulate a variety of physiological and pathological processes,i...
partly National Key R&D Program of China(2023YFA1801200,2023YFA1801202);Major Program of the National Natural Science Foundation of China(T2394532);National Natural Science Foundation of China(82072489);The Foundation of Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions(NYKFKT2019007);Shenzhen Medical Research Fund(B2302011);The Sanming Project of Medicine in Shenzhen(SZZYSM202311013);The China Postdoctoral Science Foundational,2023M743679;Shenzhen Science and Technology Research Funding(JCYJ20220818101414032);Key Research Project of Science&Technology Department of Sichuan Province,China(2024YFFK0041)。
Osteoarthritis(OA)is a degenerative joint disease accompanied with the loss of cartilage and consequent nociceptive symptoms.Normal articular cartilage maintains at aneural state.Neuron guidance factor Semaphorin 3A(S...
support of the National Natural Science Foundation of China(32025014 and 32330029 to Q.W.);the National Key Research and Development Program of China(2020YFA0804000 to Q.W.);Guangdong Excellent Youth Team Project(2024B1515040019 to Q.W.);Guangzhou Science and Technology Plan Project(202201010323 to X.H.);the Fundamental Research Funds for the Central Universities(to Q.W.).
Pharyngeal cartilage morphogenesis is crucial for the formation of craniofacial structures.Cranial neural crest cells are specified at the neural plate border,migrate to pharyngeal arches,and differentiate into pharyn...
Background: Reconstruction of Nasal Tip Columella (NTC) subunits is one of the most challenging aspects in functional aesthetic rhinoplasty. Moreover, racial variation for Asian nose rhinoplasty could even demand soph...
supported by the National Natural Science Foundation of China(52173151,82002734,51803067);the Natural Science Foundation of Guangdong Province of China(2021A1515011084,2019A1515110312);the Fundamental Research Funds for the Central Universities(22qntd1302);the Shenzhen Outbound Postdoctoral Scientific Research Fund(SZBH202108).
Cartilage tissues possess an extremely limited capacity for self-repair,and current clinical surgical approaches for treating articular cartilage defects can only provide short-term relief. Despite significantadvances...
This work was financially supported by Science and Technology Innovation Leading Plan of High-Tech Industry in Hunan Province(No.2020SK2011);The National Natural Science Foundation of China-Youth Science Fund(No.82204538);Macao Special Administrative Region Science and Technology Development Fund(No.0007/2021/AKP).
Cartilage defects are commonly observed in orthopedic clinical studies.Owing to the unique structure of cartilage tissue,current clinical treatments cannot fully address this issue.Cartilage organoids are three-dimens...