MICROCARRIERS

作品数：34被引量：100H指数：7
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相关领域：医药卫生生物学更多>>
相关期刊：《Quantitative Biology》《Regenerative Biomaterials》《Science China Chemistry》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金NSAF联合基金北京市自然科学基金中国博士后科学基金更多>>
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Injectable cartilage microtissues based on 3D cultureusing porous gelatin microcarriers for cartilagedefect treatment
《Regenerative Biomaterials》2025年第1期72-83,共12页Jing Zhu Qiuchen Luo Tiefeng Cao Guang Yang Lin Xiao 
supported by the National Natural Science Foundation of China(52173151,82002734,51803067);the Natural Science Foundation of Guangdong Province of China(2021A1515011084,2019A1515110312);the Fundamental Research Funds for the Central Universities(22qntd1302);the Shenzhen Outbound Postdoctoral Scientific Research Fund(SZBH202108).
Cartilage tissues possess an extremely limited capacity for self-repair,and current clinical surgical approaches for treating articular cartilage defects can only provide short-term relief. Despite significantadvances...
关键词：cartilage repair microtissue engineering MICROCARRIERS GELATIN BMSCS 
Integrated photothermal microcarriers for precise exosome-secreted microRNA profiling in breast cancer diagnosis
《Quantitative Biology》2024年第4期389-399,共11页Yunjie Shi Yun Cheng Peiyu Chen Lexiang Zhang Fangfu Ye 
National Key Research and Development Program of China,Grant/Award Number:2022YFA1405002;National Natural Science Foundation of China,Grant/Award Numbers:12325405,22307098;Wenzhou Institute,University of Chinese Academy of Sciences,Grant/Award Number:WIUCASQD2021012;Wenzhou high‐level innovation team;Development and application team of functional liv;Key Projects of Wenzhou Science and Technology Bureau,Grant/Award Number:ZG2023013;Wenzhou Basic Research Projects,Grant/Award Number:Y2023147;Zhejiang Provincial Natural Science Foundation of China,Grant/Award Number:LGF22C100003;Key Laboratory of Structural Malformations in Children of Zhejiang Province,Grant/Award Number:ZJET2301Z。
Breast cancer constitutes a significant global health burden,while conventional diagnosis approaches may lack precision and can be discomforting for patients.Exosomes have emerged as promising biomarkers for breast ca...
关键词：breast cancer digital PCR EXOSOMES MICRORNA PHOTOTHERMAL 
Spatiotemporal responsive hydrogel microspheres for the treatment of gastric cancer
《Aggregate》2024年第5期445-453,共9页Li Wang Lu Fan Anne M.Filppula Yu Wang Luoran Shang Hongbo Zhang 
National Natural Science Foundation of China,Grant/Award Number:82372145;Research Fellow,Grant/Award Number:353146;Research Project,Grant/Award Number:347897;Solutions for Health Profile,Grant/Award Number:336355;InFLAMES Flagship,Grant/Award Number:337531;Finland China Food and Health International Pilot project funded by Finnish MInistry of Education and Culture。
The development of tumor drug microcarriers has attracted considerable interest due to their distinctive therapeutic performances.Current attempts tend to elab-orate on the micro/nano-structure design of the microcarr...
关键词：combination therapy gastric cancer inverse opal MICROCARRIERS spatiotemporal responsiveness 
Stimuli-responsive microcarriers and their application in tissue repair: A review of magnetic and electroactive microcarrier
《Bioactive Materials》2024年第9期147-162,共16页LiYang Zhang Mengjiao Ma Junfei Li Kun Qiao Yajie Xie Yudong Zheng 
supported by National Natural Science Foundation of China(Grant No.52273119,51973018);Key Research and Development Projects of People’s Liberation Army(BWS17J036);Beijing Science and Technology Project(Z191100002019017).
Microcarrier applications have made great advances in tissue engineering in recent years, which can load cells,drugs, and bioactive factors. These microcarriers can be minimally injected into the defect to help recons...
关键词：Stimuli-responsiveness Magnetic microcarrier Electroactive microcarrier Tissue repair 
Constructing thermoresponsive PNIPAM-based microcarriers for cell culture and enzyme-free cell harvesting
《Chinese Chemical Letters》2024年第7期412-416,共5页Yunan Yuan Zhimin Luo Jie Chen Chaoliang He Kai Hao Huayu Tian 
supported by the name of National Key Research and Development Program of China(No.2021YFB3800900);the National Natural Science Foundation of China(Nos.51925305,51873208,1833010,51973217,52373161);Jilin Province Science and Technology Development Program(No.20200201075JC)。
The development of large-scale cell cultivation and non-invasive cell harvesting is highly desired in various fields,including biological regeneration and pharmaceutical research.When using traditional microcarriers f...
关键词：MICROCARRIER Temperature-responese PNIPAM Polymers Cell culture 
Biosynthesis of fungus-based oral selenium microcarriers for radioprotection and immuno-homeostasis shaping against radiation-induced heart disease
《Bioactive Materials》2024年第7期393-406,共14页Chang Liu Weiyi Wang Haoqiang Lai Yikang Chen Lvyi Li Haiwei Li Meixiao Zhan Tianfeng Chen Wenqiang Cao Xiaoling Li 
supported by the National Science Fund for Distinguished Young Scholars (82225025);National Natural Science Foundation of China (21877049,32171296,32101044);Guangdong Natural Science Foundation (2020B1515120043);K.C.Wong Education Foundation and China Postdoctoral Science Foundation (2022M711341).
Radiation-induced heart disease(RIHD),characterized by severe oxidative stress and immune dysregulation,is a serious condition affecting cancer patients undergoing thoracic radiation.Unfortunately,clinical interventio...
关键词：Radiation-induced heart disease Antioxidant SELENIUM SELENOPROTEIN Heart protection 
One-step cell biomanufacturing platform:porous gelatin microcarrier beads promote human embryonic stem cell-derived midbrain dopaminergic progenitor cell differentiation in vitro and survival after transplantation in vivo被引量：1
《Neural Regeneration Research》2024年第2期458-464,共7页Lin Feng Da Li Yao Tian Chengshun Zhao Yun Sun Xiaolong Kou Jun Wu Liu Wang Qi Gu Wei Li Jie Hao Baoyang Hu Yukai Wang 
supported by the National Key Research and Development Program of China,Nos.2017YFE0122900(to BH),2019YFA0110800(to WL),2019YFA0903802(to YW),2021YFA1101604(to LW),2018YFA0108502(to LF),and 2020YFA0804003(to JW);the National Natural Science Foundation of China,Nos.31621004(to WL,BH)and 31970821(to YW);CAS Project for Young Scientists in Basic Research,No.YSBR-041(to YW);Joint Funds of the National Natural Science Foundation of China,No.U21A20396(to BH)。
Numerous studies have shown that cell replacement therapy can replenish lost cells and rebuild neural circuitry in animal models of Parkinson’s disease.Transplantation of midbrain dopaminergic progenitor cells is a p...
关键词：axonal integrity cell cryopreservation cellular environment cellular niche cell replacement therapy dopaminergic progenitors human pluripotent stem cell mechanical damage neuronal cell delivery Parkinson’s disease small-aperture gelatin microcarriers 
Microcarriers promote the through interface movement of mouse trophoblast stem cells by regulating stiffness被引量：2
《Bioactive Materials》2023年第10期196-205,共10页Zili Gao Jia Guo Bo Gou Zhen Gu Tan Jia Sinan Ma Liyuan Jiang Wenli Liu Lixun Zhou Qi Gu 
supported by National Natural Science Foundation of China(T2222029 and U21A20396);Strategic Priority Research Program of Chinese Academy of Sciences(XDA16020802);CAS Project for Young Scientists in Basic Research(YSBR-012);CAS Engineering Laboratory for Intelligent Organ Manufacturing(KFJ-PTXM-039).
Mechanical force is crucial in the whole process of embryonic development.However,the role of trophoblast mechanics during embryo implantation has rarely been studied.In this study,we constructed a model to explore th...
关键词：BIOMECHANICS MICROCARRIERS Embryo implantation Cell migration 
Stem cell niche-inspired microcarriers with ADSCs encapsulation for diabetic wound treatment被引量：2
《Bioactive Materials》2023年第8期159-168,共10页Xiangyi Wu Haofang Zhu Junyi Che Ye Xu Qian Tan Yuanjin Zhao 
supported by the National Key Research and Development Program of China(2020YFA0908200);the National Natural Science Foundation of China(81974288,T2225003 and 52073060);the Strategic Priority Research Program of the Chinese Academy of Science(XDA16021103);the Guangdong Basic and Applied Basic Research Foundation(2021B1515120054);the Shenzhen Fundamental Research Program(JCYJ20190813152616459 and JCYJ20210324133214038).
Stem cell therapies have made great progress in the treatment of diabetic wounds during recent decades,while their short in vivo residence,alloimmune reactions,undesired behaviors,and dramatic losses of cell functions...
关键词：Stem cell BIO-INSPIRED Microfluidics MICROCARRIER Wound healing Hydrogel 
Antibacterial hydrogel with pH-responsive microcarriers of slow-release VEGF for bacterial infected wounds repair被引量：2
《Journal of Materials Science & Technology》2023年第13期198-212,共15页Xiaofei Xie Huan Lei Daidi Fan 
Bacterial infection causes wound inflammation and makes angiogenesis difficult.It is urgent to develop effectively antibacterial and pro-vascularizing dressings for wound healing.The hydrogel is developed with pH-resp...
关键词：ANTIBACTERIAL pH-responsive microcarriers Slow-release Infected wound repair 
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