MICROCARRIER

作品数:26被引量:53H指数:5
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相关领域:医药卫生更多>>
相关作者:洪丰王全义彭存旭张秋生杨永红更多>>
相关机构:济宁医学院首都医科大学附属北京佑安医院山东大学山东省寄生虫病防治研究所更多>>
相关期刊:《Chinese Medical Journal》《Science China Materials》《Frontiers of Materials Science》《Science Bulletin》更多>>
相关基金:国家自然科学基金NSAF联合基金更多>>
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Stimuli-responsive microcarriers and their application in tissue repair: A review of magnetic and electroactive microcarrier
《Bioactive Materials》2024年第9期147-162,共16页LiYang Zhang Mengjiao Ma Junfei Li Kun Qiao Yajie Xie Yudong Zheng 
supported by National Natural Science Foundation of China(Grant No.52273119,51973018);Key Research and Development Projects of People’s Liberation Army(BWS17J036);Beijing Science and Technology Project(Z191100002019017).
Microcarrier applications have made great advances in tissue engineering in recent years, which can load cells,drugs, and bioactive factors. These microcarriers can be minimally injected into the defect to help recons...
关键词:Stimuli-responsiveness Magnetic microcarrier Electroactive microcarrier Tissue repair 
Multifunctional inverse opal microcarriers-based cytokines delivery system with stem cell homing capability for osteoarthritis treatment
《Aggregate》2024年第4期199-207,共9页Lingyu Sun Jingjing Gan Lijun Cai Feika Bian Wei Xu Yuanjin Zhao 
National Key Research and Development Program of China,Grant/Award Number:2020YFA0908200;National Natural Science Foundation of China,Grant/Award Numbers:T2225003,52073060,61927805,82302398,82272165;Guangdong Basic and Applied Basic Research Foundation,Grant/Award Number:2021B1515120054;Shenzhen Fundamental Research Program,Grant/Award Numbers:JCYJ20190813152616459,JCYJ20210324133214038;Jiangsu Funding Program for Excellent Postdoctoral Talent,Grant/Award Number:2022ZB710;China Postdoctoral Science Foundation,Grant/Award Numbers:2022TQ0145,2022M721581。
Osteoarthritis has been regarded as a complex and serious degenerative disease.Attempts in this area are focused on improving the curative effect of stem cell-based therapies.In this work,we present a novel inverse op...
关键词:CYTOKINE hydrogel inverse opal MICROFLUIDICS OSTEOARTHRITIS stem cell homing 
Constructing thermoresponsive PNIPAM-based microcarriers for cell culture and enzyme-free cell harvesting
《Chinese Chemical Letters》2024年第7期412-416,共5页Yunan Yuan Zhimin Luo Jie Chen Chaoliang He Kai Hao Huayu Tian 
supported by the name of National Key Research and Development Program of China(No.2021YFB3800900);the National Natural Science Foundation of China(Nos.51925305,51873208,1833010,51973217,52373161);Jilin Province Science and Technology Development Program(No.20200201075JC)。
The development of large-scale cell cultivation and non-invasive cell harvesting is highly desired in various fields,including biological regeneration and pharmaceutical research.When using traditional microcarriers f...
关键词:MICROCARRIER Temperature-responese PNIPAM Polymers Cell culture 
Hydrogel-supported poly(L-lactic acid) and polystyrene microsphere-based three-dimensional culture systems for in vitro cell expansion
《Frontiers of Materials Science》2024年第2期129-137,共9页Huaying Hao Lihong Sun Jiaxuan Chen Jun Liang 
supported by the National Key Research andDevelopment Program of China(Grant No.2021YFC2101400).
The in vitro expansion of stem cells is important for their application in different life science fields such as cellular tissue and organ repair.An objective of this paper was to achieve static cell culture in vitro ...
关键词:MICROCARRIER MICROSPHERE peptide hydrogel cell scaffold three-dimensional culture cell expansion 
One-step cell biomanufacturing platform:porous gelatin microcarrier beads promote human embryonic stem cell-derived midbrain dopaminergic progenitor cell differentiation in vitro and survival after transplantation in vivo被引量:1
《Neural Regeneration Research》2024年第2期458-464,共7页Lin Feng Da Li Yao Tian Chengshun Zhao Yun Sun Xiaolong Kou Jun Wu Liu Wang Qi Gu Wei Li Jie Hao Baoyang Hu Yukai Wang 
supported by the National Key Research and Development Program of China,Nos.2017YFE0122900(to BH),2019YFA0110800(to WL),2019YFA0903802(to YW),2021YFA1101604(to LW),2018YFA0108502(to LF),and 2020YFA0804003(to JW);the National Natural Science Foundation of China,Nos.31621004(to WL,BH)and 31970821(to YW);CAS Project for Young Scientists in Basic Research,No.YSBR-041(to YW);Joint Funds of the National Natural Science Foundation of China,No.U21A20396(to BH)。
Numerous studies have shown that cell replacement therapy can replenish lost cells and rebuild neural circuitry in animal models of Parkinson’s disease.Transplantation of midbrain dopaminergic progenitor cells is a p...
关键词:axonal integrity cell cryopreservation cellular environment cellular niche cell replacement therapy dopaminergic progenitors human pluripotent stem cell mechanical damage neuronal cell delivery Parkinson’s disease small-aperture gelatin microcarriers 
Stem cell niche-inspired microcarriers with ADSCs encapsulation for diabetic wound treatment被引量:2
《Bioactive Materials》2023年第8期159-168,共10页Xiangyi Wu Haofang Zhu Junyi Che Ye Xu Qian Tan Yuanjin Zhao 
supported by the National Key Research and Development Program of China(2020YFA0908200);the National Natural Science Foundation of China(81974288,T2225003 and 52073060);the Strategic Priority Research Program of the Chinese Academy of Science(XDA16021103);the Guangdong Basic and Applied Basic Research Foundation(2021B1515120054);the Shenzhen Fundamental Research Program(JCYJ20190813152616459 and JCYJ20210324133214038).
Stem cell therapies have made great progress in the treatment of diabetic wounds during recent decades,while their short in vivo residence,alloimmune reactions,undesired behaviors,and dramatic losses of cell functions...
关键词:Stem cell BIO-INSPIRED Microfluidics MICROCARRIER Wound healing Hydrogel 
基于microcarrier 6正常免疫鼠人源宫颈癌移植瘤模型的构建及其临床应用意义被引量:1
《中国实验诊断学》2022年第4期572-577,共6页刘昆燕 张秋实 张凯 洪丰 王全义 彭一晴 赵影 段亚楠 周润生 彭存旭 
国家自然科学基金(81170395、81570556)。
目的 基于新型3D微载体(microcarrier 6),复合人原代宫颈癌细胞,皮下接种于具有正常免疫功能的小鼠,以期建立新型宫颈癌人源肿瘤移植瘤动物模型(PDX),并分析正常免疫鼠移植瘤病理学特点。方法 将75只雌性C57BL/6小鼠按移植物不同随机分...
关键词:子宫颈肿瘤 原代肿瘤 MICROCARRIER 免疫 异种移植 动物模型 
基于Microcarrier 6构建正常免疫小鼠人源肿瘤异种移植模型被引量:1
《中华实验外科杂志》2020年第3期516-516,共1页唐慧昕 毕研贞 洪丰 
国家自然科学基金 (81170395、81570556)。
本研究利用新型微载体Microcarrier 6成功构建人来源的正常免疫小鼠移植瘤模型,现报道如下。一、材料与方法将人源肿瘤细胞与经修饰过的Microcarrier 6共培养24 h,测量小鼠成瘤时间及成瘤体积。应用SPSS 20.0统计软件学分析,计量资料以...
关键词:异型细胞 移植瘤模型 瘤体积 免疫组织化学 成瘤率 微载体 肿瘤细胞 计量资料 
Tofu-inspired microcarriers from droplet microfluidics for drug delivery被引量:5
《Science China Chemistry》2019年第1期87-94,共8页Han Zhang Yuxiao Liu Jie Wang Changmin Shao Yuanjin Zhao 
supported by the National Natural Science Foundation of China(21473029,51522302);the National Scholastic Athletics Foundation of China(U1530260);the Scientific Research Foundation of Southeast University
Microcarriers have attracted increasing interests in drug delivery. In order to develop this technique, it is prone to focus on the generation of functional particles through using simple approaches and novel but acce...
关键词:TOFU MICROFLUIDICS MICROCARRIER DRUG delivery particle DROPLET 
正常免疫鼠人原代卵巢癌模型的建立被引量:6
《现代妇产科进展》2018年第12期901-904,共4页黄蓉 洪丰 毕研贞 王云飞 舒振锋 石秀玲 杨飞 王卫 彭存旭 
国家自然科学基金(No:81170395;81570556;81502255)
目的:正常免疫小鼠皮下接种人原代卵巢癌细胞与微载体(microcarrier 6)复合体,建立正常免疫鼠人原代卵巢癌模型。方法:将36只C57BL/6雌鼠按是否将人原代卵巢癌细胞与微载体共同培养随机分为原代卵巢癌细胞组、空载体组和三维原代卵巢癌...
关键词:卵巢癌 MICROCARRIER 动物模型 皮下移植瘤 
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