National Natural Science Foundation of China(No.22101133);Natural Science Foundation of Jiangsu Province(No.BK20200768)and Nanjing Forestry University are greatly acknowledged.
An efficiently catalytic method toward the synthesis of indolin-2-ones featuring an allylic derived C_(3)-quaternary stereocenter via an intramolecular Heck cyclization/Suzuki coupling of N-substituted-N-(2-bromopheny...
supported by the National Natural Science Foundation of China(No.21971212);the Key Project of Innovation Research 2035 Pilot Plan of Southwest University(SWU-XDZD22007).
A type of unique azole-hybridized acylhydrazonyl aloe emodins(AAEs)were developed as new antibacterial agents for combating bacterial infections.Some target AAEs showed strong antibacterial activities,especially,tetra...
supported by the National Natural Science Foundation of China(NSFC,grant nos.22050005,21920102001,22171160,and 22371161);Tsinghua University Dushi Program,and China National Postdoctoral Program for Innovative Talents(grant no.BX20220184).
hydrocarbon belts due to their potential applications in carbon nanotechnology.By contrast,heteroatomembedded zigzag hydrocarbon belts as advanced design strategies with fascinating structures and desirable,unique pro...
supported by the National Natural Science Foundation of China(21932006);the China Postdoctoral Science Foundation(2019M652058)
Synthetic N-heterocyclic compounds,such as quinoxalines,have shown a crucial role in pharmaceutical as well as food and dye industries.However,the traditional synthesis toward N-heterocycles relies on multistep energy...
supported by the National Key Research and Development Program of China(2022YFA1502902);the National Natural Science Foundation of China(22371215,22222111,21971198);the Guangdong Basic and Applied Basic Research Foundation(2022A1515012614);the Large-scale Instrument and Equipment Sharing Foundation of Wuhan University;China Postdoctoral Science Foundation(2022M722451)for the financial support。
Construction of axially chiral 1-azafluorenes via nickel-catalyzed[2+2+2]cycloaddition of alkynes and(o-alkynyl)benzyl nitriles is described.This strategy enables enantioselective discrimination of two sterically simi...
Inflammation represents an initial response of immune system and is involved in a number of biochemical inci-dents.Such incidents may multiply and further develop the provocative response.Over the past 15 years,variou...
support from the National Natural Science Foundation of China[No.22075143,21875110];the Science Challenge Project[TZ2018004];the Qing Lan Project for the grant。
In this study,a new energetic hybrid skeleton was constructed through the integration of nitropyrazole and 1,3,4-oxadiazole skeletons in a molecule.Furthermore,the energetic precursor(2),the azo-bridged compound(3),th...
the National Natural Science Foundation of China (No. 22071001);The Research Culture Funds of Anhui Normal University;Department of Human Resources of Anhui Province for financial support。
A novel method for HDDA-derived benzyne trapped by nitrone was developed. This research described a simple and efficient pathway for the synthesis of benzisoxazoles from arynes and PTIO(2-phenyl-4,4,5,5-tetramethylimi...
Financial support by the National Natural Science Foundation of China(No.22071211);the Science and Technology Planning Project of Hunan Province(No.2019RS2039);Hunan Provincial Natural Science Foundation of China(No.2020JJ3032);Scientific Research Fund of Education Department of Hunan Province(No.21A0079);Open Research Fund of School of Chemistry and Chemical Engineering of Henan Normal University(No.2022C02)。
O-Acyl ketoximes has been proven to be versatile building blocks for practical construction of Nheterocycles.In the last few years,diverse catalytic systems have been discovered to enable efficient transformations of ...
We gratefully acknowledge HKBU RC-Tier 2 Start-up Grant for financial support.
An efficient and practical synthesis of heterocyclic nucleosides is developed by a catalyst-free highly regioselective and diastereose-lective[3+2]annulation of a-purine-substituted acrylates with nitrones.The reactio...