Objectives To compare the effectiveness and safety of oral misoprostol 50 µg three doses, 4 hours apart vs. intravaginal PGE2 (Dinoprostone) 3 mg two doses 8 hours apart for pre-induction cervical ripening in women w...
supported by grants from National Natural Science Foundation of China (No.31860728 and 32172961);Special Fund for Ocean and Fisheries of Xiamen (No.21CZY018HJ01).
Prostaglandin E2(PGE2)has been reported to be involved in reproduction as one of the most abundant and widely distributed prostaglandins in invertebrates.Regulating gonad development and gamete production in mollusks ...
supported by Grants-in-Aid for Scientific Research on Priority Areas from the Ministry of Education,Culture,Sports,Science and Technology of Japan(JSPS KAKENHI grant number 20K06719 to TT);We also acknowledge a scholarship from Bangabandhu Science and Technology Fellowship Trust,Ministry of Science and Technology,Government of the People’s Republic of Bangladesh for Saokat Ahamed(memo no:08//04-01-2021).
The main neuroendocrine pathways of induction of reproductive behavior in fish are elucidated.17α,20β-dihydroxy-4-pregnen-3-one (17,20β-DHP),an oocyte maturation-inducing hormone,was found to act as a pheromone to ...
National Yang Ming Chiao Tung University Far Eastern Memorial Hospital Joint Research Programs(NYCU-FEMH 109DN03,110DN06,111DN04,112DN05).
Hepatocellular carcinoma(HCC)is a leading cause of death worldwide.Current therapies are effective for HCC patients with early disease,but many patients suffer recurrence after surgery and have a poor response to chem...
the S and T Program of Hebei,No.22377704D;Medical Science Research Project of Hebei Province,No.20190510;Postgraduate’s Innovation Fund Project of Hebei Province,No.CXZZBS2021077.
BACKGROUND Oxaliplatin(Oxa)is the first-line chemotherapy drug for colorectal cancer(CRC),and Oxa resistance is crucial for treatment failure.Prostaglandin F_(2α)synthase(PGF 2α)(PGFS),an enzyme that catalyzes the p...
Objective To quantify phytochemicals using liquid chromatography and mass spectroscopy(LCMS)analysis and explore the therapeutic effect of Aesculus hippocastanum L.(AH)seeds ethanolic extract against gastric ulcers in...
supported by the Natural Science Foundation of Shandong Province(ZR2020MH327);Hebei Key Research and Development Program(19272405D);Jilin Scientific and Technological Development Program(Grant No.20190304041YY).
Mesenchymal stem cells(MSCs)have been widely used in regenerative medicine and clinical therapy due to their capabilities of proliferation,differentiation,and immune regulation.However,during in vitro expansion,MSCs a...
Objective To study and analyze the status of patent protection of prostaglandin analogues for glaucoma in China.Methods Patent literatures published up to April 7,2020 were retrieved by the keywords“PG”and“prostagl...
We would like to thank Prof.Richard J.Youle(US National Institute of Neurological Disorders and Stroke)and Prof.Myung-Shik Lee(Yonsei University College of Medicine)for providing TFEB knockout HeLa cells.We thank Martha Dahlen for the English editing.This study was supported by the Hong Kong General Research Fund(GRF/HKBU12101417,GRF/HKBU12100618);the National Natural Science Foundation of China(81703487,and 81773926);Shenzhen Science and Technology Innovation Commission(JCYJ20180302174028790,JCYJ20180507184656626);the Hong Kong Health and Medical Research Fund(HMRF17182541,HMRF17182551);research funds from Hong Kong Baptist University(HKBU/RC-IRCs/17-18/03).
Transcriptional factor EB(TFEB),a master regulator of autophagy and lysosomal biogenesis,is generally regarded as a pro-survival factor.Here,we identify that besides its effect on autophagy induction,TFEB exerts a pro...
Shandong natural science foundation(No.ZR2019MH083);National Famous and Old Chinese Medicine Expert Li Guangwen Inheritance Studio;Wang Dongmei Shandong Province Famous and Old Chinese Medicine Expert Inheritance Studio。
Objective:Explore the role of Th1/Th2 balance in the pathogenesis of primary dysmenorrhea through study the effect of Th1/Th2 balance drift on serum prostaglandin F_(2α),prostaglandin,6-keto-prostaglandin F_(1α),TXB...