Understanding neuroendocrine regulatory pathways of sexual behavior in teleosts  

作　　者：Saokat Ahamed Toshinobu Tokumoto 

机构地区：[1]Department of Bioscience,Graduate School of Science and Technology,Shizuoka University,Ohya 836,Suruga-ku,Shizuoka,422-8529,Japan

出　　处：《Aquaculture and Fisheries》2024年第3期447-454,共8页渔业学报（英文）

基　　金：supported by Grants-in-Aid for Scientific Research on Priority Areas from the Ministry of Education,Culture,Sports,Science and Technology of Japan(JSPS KAKENHI grant number 20K06719 to TT);We also acknowledge a scholarship from Bangabandhu Science and Technology Fellowship Trust,Ministry of Science and Technology,Government of the People’s Republic of Bangladesh for Saokat Ahamed(memo no:08//04-01-2021).

摘　　要：The main neuroendocrine pathways of induction of reproductive behavior in fish are elucidated.17α,20β-dihydroxy-4-pregnen-3-one (17,20β-DHP),an oocyte maturation-inducing hormone,was found to act as a pheromone to induce male reproductive behavior.17α,20β-DHP-sulfate (17,20β-DHP-S),a derivative of 17,20β-DHP,was also identified as a later-acting pheromone.In addition,prostaglandin F2 alpha (PGF2α),which is synthesized during female ovulation,has been shown to also act as a pheromone,inducing the final oviposition-inducing behavior to make fertilization successful.It appears that these molecular events are initiated by stimuli from the brain.Numerous neuropeptides have been discovered that promote the initiation of reproductive behavior.Recently,with the proliferation of genome editing technology,a detailed analysis of the molecules involved in these pathways is underway.Analysis of gene knockout in zebrafish and medaka is actively underway.On the other hand,many research reports have shown that the induction pathways of male reproductive behavior are adversely affected by chemical substances.Knowledge of the adverse effects of chemical substances is not only useful as information to prevent their mixing from the viewpoint of protecting the natural environment and as a point of caution in fish farming,but also provides clues for elucidating the pathways of reproductive behavior induction.The elucidation of the pathways of reproductive behavior induction is also important from the point of view of breeding technology for fish farming and biodiversity conservation.In this review,we summarize recent research on the pathways of male reproductive behavior induction in fish and the possibility of developing new aquaculture techniques depending on the results.

关 键 词：Fish male reproductive behavior Steroid hormone PHEROMONE 17 20β-DHP PROSTAGLANDIN GOLDFISH ZEBRAFISH CRISPR/Cas9 

分 类 号：S917[农业科学—水产科学]