supported by the National Natural Science Foundation of China(22377103,22107090 and 22077110);the Natural Science Foundation of Jiangsu Province(BK20200106);the Major Basic Research Project of the Natural Science Research Foundation of the Jiangsu Higher Education Institutions(20KJA350001);the Natural Science Research Project of Jiangsu Universities(21KJB350009);the Scientific Research Foundation for Talented Scholars in Xuzhou Medical University(D2020036,D2022002).
The vasopressin V_(2)receptor(V_(2)R)is a validated therapeutic target for autosomal dominant polycystic kidney disease(ADPKD),with tolvaptan being the first FDA-approved antagonist.Herein,we used Gaussian accelerated...
the National Natural Science Foundation of China(Nos.82071974,82102107,and 82371998);the Science and Technology Program of Guangzhou,China(Nos.202206010106 and 2023A04J1921);the Guangdong Science and Technology Planning Project,China(2022A0505050042).
The arginine-vasopressin(AVP)hormone plays a pivotal role in regulating various physiological processes,such as hormone secretion,cardiovascular modulation,and social behavior.Recent studies have highlighted the V1a r...
Septic shock treatment remains a major challenge for intensive care units,despite the recent prominent advances in both management and outcomes.Vasopressors serve as a cornerstone of septic shock therapy,but there is ...
BACKGROUND Arginine vasopressin is a neuropeptide produced in the hypothalamus and released by the posterior pituitary gland.In addition to maintaining plasma osmolarity,under hypovolemic or hypotensive conditions,it ...
OBJECTIVES To assess the effect of vasopressin,steroid and epinephrine(VSE)combination therapy on return of spontan-eous circulation(ROSC)after in-hospital cardiac arrest(IHCA),and test the conclusiveness of evidence ...
This Research Highlight was supported by grants from the USA:AG058603 from the National Institute of Aging;National Institutes of Health;and AHA00169 from the American Heart Association.
Social animals prefer to live in groups and transfer social signals to share their physical or psychological distress and seek comfort[1,2].During this process,social buffering is an essential concept in social networ...
Shandong natural science foundation(No.ZR2019MH083);National Famous and Old Chinese Medicine Expert Li Guangwen Inheritance Studio;Wang Dongmei Shandong Province Famous and Old Chinese Medicine Expert Inheritance Studio。
Objective:Explore the role of Th1/Th2 balance in the pathogenesis of primary dysmenorrhea through study the effect of Th1/Th2 balance drift on serum prostaglandin F_(2α),prostaglandin,6-keto-prostaglandin F_(1α),TXB...
supported by grants from the National Natural Science Foundation of China (31271215, 81770423, 81973945, and 81673766);the Health Vocational and Technical Education Research Program of Jiangsu Province, China (J201506)。
The present study was designed to investigate the mechanisms by which P2X7 receptors(P2X7Rs)mediate the activation of vasopressinergic neurons thereby increasing sympathetic hyperactivity in the paraventricular nucleu...
To the Editor:Myomectomy is an important treatment option for removing a hysteromyoma,along with intra-myometrial vasopressin to reduce intraoperative bleeding.[1,2]Sometimes,however,it results in life-threatening com...
This study was supported by the grant from Strategic Priority Research Program of the Chinese Academy of Sciences(XDB11050300);The Inner Mongolia Research Station of Animal Ecology and International Society of Zoological Sciences provided help and assistance for the field works.
It is known that social stress could alter oxytocin(OT)and arginine-vasopressin(AVP)expression in specific regions of brains which regulate the aggressive behavior of small rodents,but the effects of density-induced s...