VASOPRESSIN

作品数:64被引量:110H指数:6
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相关领域:医药卫生更多>>
相关作者:姚泰朱珠于勇向正华曹鲁乡更多>>
相关机构:上海医科大学贵州大学福建医科大学第二军医大学更多>>
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相关基金:国家自然科学基金浙江省卫生厅资助项目中国博士后科学基金北京市自然科学基金更多>>
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Structural basis of tolvaptan binding to the vasopressin V_(2)receptor
《Acta Pharmacologica Sinica》2024年第11期2441-2449,共9页Hong-li Liu Hai-yang Zhong Yi-xiao Zhang Hua-rui Xue Zheng-shuo Zhang Ke-quan Fu Xu-dong Cao Xiao-chun Xiong Dong Guo 
supported by the National Natural Science Foundation of China(22377103,22107090 and 22077110);the Natural Science Foundation of Jiangsu Province(BK20200106);the Major Basic Research Project of the Natural Science Research Foundation of the Jiangsu Higher Education Institutions(20KJA350001);the Natural Science Research Project of Jiangsu Universities(21KJB350009);the Scientific Research Foundation for Talented Scholars in Xuzhou Medical University(D2020036,D2022002).
The vasopressin V_(2)receptor(V_(2)R)is a validated therapeutic target for autosomal dominant polycystic kidney disease(ADPKD),with tolvaptan being the first FDA-approved antagonist.Herein,we used Gaussian accelerated...
关键词:vasopressin V_(2)receptor(V_(2)R) TOLVAPTAN binding pathway gaussian accelerated molecular dynamics(GaMD)simulations 
Discovery and evaluation of a novel ^(18)F-labeled vasopressin 1a receptor PET ligand with peripheral binding specificity
《Acta Pharmaceutica Sinica B》2024年第9期4014-4027,共14页Junqi Hu Yinlong Li Chenchen Dong Huiyi Wei Kai Liao Junjie Wei Chunyu Zhao Ahmad Chaudhary Jiahui Chen Hao Xu Ke Zhong Steven H.Liang Lu Wang Weijian Ye 
the National Natural Science Foundation of China(Nos.82071974,82102107,and 82371998);the Science and Technology Program of Guangzhou,China(Nos.202206010106 and 2023A04J1921);the Guangdong Science and Technology Planning Project,China(2022A0505050042).
The arginine-vasopressin(AVP)hormone plays a pivotal role in regulating various physiological processes,such as hormone secretion,cardiovascular modulation,and social behavior.Recent studies have highlighted the V1a r...
关键词:VASOPRESSIN AUTISM V1a receptor Positron emission tomography PET imaging RADIOLABELING Fluorine 18 Kinetic modeling 
Should we initiate vasopressors earlier in patients with septic shock: A mini systemic review
《World Journal of Critical Care Medicine》2023年第4期204-216,共13页Hang-Xiang Zhou Chun-Fu Yang He-Yan Wang Yin Teng Hang-Yong He 
Septic shock treatment remains a major challenge for intensive care units,despite the recent prominent advances in both management and outcomes.Vasopressors serve as a cornerstone of septic shock therapy,but there is ...
关键词:Septic shock RESUSCITATION VASOPRESSOR NOREPINEPHRINE VASOPRESSIN Timing 
Vasopressin-induced hyponatremia in an adult normotensive trauma patient:A case report被引量:1
《World Journal of Critical Care Medicine》2023年第1期35-40,共6页Maulik K Lathiya Emily Pepperl Daniel Schaefer Hussam Al-Sharif Adel Zurob Susan M Cullinan Antonios Charokopos 
BACKGROUND Arginine vasopressin is a neuropeptide produced in the hypothalamus and released by the posterior pituitary gland.In addition to maintaining plasma osmolarity,under hypovolemic or hypotensive conditions,it ...
关键词:HYPONATREMIA VASOPRESSIN NORMOTENSIVE Therapy Case report 
Efficacy of vasopressin, steroid, and epinephrine protocol for in-hospital cardiac arrest resuscitation: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis
《Journal of Geriatric Cardiology》2022年第9期705-711,共7页Danish Iltaf Satti Yan Hiu Athena Lee Keith Sai Kit Leung Jeremy Man Ho Hui Thompson Ka Ming Kot Arslan Babar Gauranga Mahalwar Abraham KC Wai Tong Liu Leonardo Roever Gary Tse Jeffrey Shi Kai Chan International Health Informatics Study(IHIS)Network 
OBJECTIVES To assess the effect of vasopressin,steroid and epinephrine(VSE)combination therapy on return of spontan-eous circulation(ROSC)after in-hospital cardiac arrest(IHCA),and test the conclusiveness of evidence ...
关键词:RESUSCITATION analysis RETURN 
Vasopressin Signaling Buffers Synaptic Metaplasticity in a Sex-specific Manner
《Neuroscience Bulletin》2021年第9期1377-1380,共4页Luodan Yang Lorelei Tucker Quanguang Zhang 
This Research Highlight was supported by grants from the USA:AG058603 from the National Institute of Aging;National Institutes of Health;and AHA00169 from the American Heart Association.
Social animals prefer to live in groups and transfer social signals to share their physical or psychological distress and seek comfort[1,2].During this process,social buffering is an essential concept in social networ...
关键词:BUFFERS networks. DISTRESS 
Effect of Th1/Th2 balance on serum prostaglandin,COX-2,AVP and OT in primary dysmenorrhea rats with cold coagulation and blood stasis syndrome
《Journal of Hainan Medical University》2021年第15期1-5,共5页Feng-Ting Zhai Dong-Mei Wang Qing Ma Wei-Ping Cao Dan-Dan Wang Guang-Wen Li 
Shandong natural science foundation(No.ZR2019MH083);National Famous and Old Chinese Medicine Expert Li Guangwen Inheritance Studio;Wang Dongmei Shandong Province Famous and Old Chinese Medicine Expert Inheritance Studio。
Objective:Explore the role of Th1/Th2 balance in the pathogenesis of primary dysmenorrhea through study the effect of Th1/Th2 balance drift on serum prostaglandin F_(2α),prostaglandin,6-keto-prostaglandin F_(1α),TXB...
关键词:Primary dysmenorrhea Th1/Th2 balance PROSTAGLANDIN CYCLOOXYGENASE-2 VASOPRESSIN OXYTOCIN 
Paraventricular Nucleus P2X7 Receptors Aggravate Acute Myocardial Infarction Injury via ROS-Induced Vasopressin-V1b Activation in Rats被引量:3
《Neuroscience Bulletin》2021年第5期641-656,共16页Wenjing Cheng Yinggang Sun Qin Wu Kokwin Ooi Yi Feng Chunmei Xia Danian Zhu 
supported by grants from the National Natural Science Foundation of China (31271215, 81770423, 81973945, and 81673766);the Health Vocational and Technical Education Research Program of Jiangsu Province, China (J201506)。
The present study was designed to investigate the mechanisms by which P2X7 receptors(P2X7Rs)mediate the activation of vasopressinergic neurons thereby increasing sympathetic hyperactivity in the paraventricular nucleu...
关键词:PVN P2X7 receptor VASOPRESSIN Reactive oxygen species C-FOS Myocardial ischemia 
Intramyometrial injection of vasopressin resulting in severe bradycardia during myomectomy
《Chinese Medical Journal》2021年第7期862-863,共2页Li-Ping Song Shi-Miao Feng Xiao-Qin Jiang 
To the Editor:Myomectomy is an important treatment option for removing a hysteromyoma,along with intra-myometrial vasopressin to reduce intraoperative bleeding.[1,2]Sometimes,however,it results in life-threatening com...
关键词:INJECTION MEC CARDIA 
Density-induced social stress alters oxytocin and vasopressin activities in the brain of a small rodent species被引量:1
《Integrative Zoology》2021年第2期149-159,共11页Shuli HUANG Guoliang LI Yongliang PAN Mingjing SONG Jidong ZHAO Xinrong WAN Charles JKREBS Zuoxin WANG Wenxuan HAN Zhibin ZHANG 
This study was supported by the grant from Strategic Priority Research Program of the Chinese Academy of Sciences(XDB11050300);The Inner Mongolia Research Station of Animal Ecology and International Society of Zoological Sciences provided help and assistance for the field works.
It is known that social stress could alter oxytocin(OT)and arginine-vasopressin(AVP)expression in specific regions of brains which regulate the aggressive behavior of small rodents,but the effects of density-induced s...
关键词:aggression behavior density-dependent stress oxytocin(OT) social stress vasopressin(AVP) 
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