云南高校图书馆联盟文献共享服务平台- RADIOLABELING

RADIOLABELING: 作品数：22被引量：16H指数：3; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关期刊：《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Chinese Medical Journal》《International Journal of Organic Chemistry》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金中国科学院知识创新工程更多>>

Discovery and evaluation of a novel ^(18)F-labeled vasopressin 1a receptor PET ligand with peripheral binding specificity: 《Acta Pharmaceutica Sinica B》2024年第9期4014-4027,共14页Junqi Hu Yinlong Li Chenchen Dong Huiyi Wei Kai Liao Junjie Wei Chunyu Zhao Ahmad Chaudhary Jiahui Chen Hao Xu Ke Zhong Steven H.Liang Lu Wang Weijian Ye; the National Natural Science Foundation of China(Nos.82071974,82102107,and 82371998);the Science and Technology Program of Guangzhou,China(Nos.202206010106 and 2023A04J1921);the Guangdong Science and Technology Planning Project,China(2022A0505050042).; The arginine-vasopressin(AVP)hormone plays a pivotal role in regulating various physiological processes,such as hormone secretion,cardiovascular modulation,and social behavior.Recent studies have highlighted the V1a r...; 关键词：VASOPRESSIN AUTISM V1a receptor Positron emission tomography PET imaging RADIOLABELING Fluorine 18 Kinetic modeling

Peptides Radiofluorination: Main Methods and Highlights: 《International Journal of Organic Chemistry》2022年第4期161-172,共12页Ana Carolina A. Bispo Fernanda A. F. Almeida Juliana B. Silva Marcelo Mamede; Peptides have an important role in organism and its high quantity present in tumors leading to development of radiolabeled peptides for tumor-specific imaging. Once the traditional methodologies used for radiofluorina...; 关键词：RADIOFLUORINATION RADIOLABELING PEPTIDES Prosthetic Groups FLUORINE-18

Isolation of ^(212)Pb from natural thorium for targeted alpha-therapy被引量：1: 《Chinese Chemical Letters》2022年第7期3474-3477,共4页Junyi Chen Mengxin Xu Yu Liu Dongban Duan Yuxiang Han Zhibo Liu; funded by Beijing Municipal Natural Science Foundation (No. Z200018);the Special Foundation of Beijing Municipal Education Commission (No. 3500–12020123);the National Natural Science Foundation of China (Nos. U1867209 and 21778003);the Ministry of Science and Technology of the People’s Republic of China (No. 2017YFA0506300);Li Ge-Zhao Ning Life Science Youth Research Foundation (No. LGZNQN202004)。; Targeted alpha-therapy(TAT) is increasingly attractive due to its extraordinary antitumor efficacy.However,the supply of α-emitters for TAT is insufficient and under control by a limited number of countries.^(212)Pb ...; 关键词：^(212)Pb Targeted alpha-therapy RADIOLABELING Radionuclide generator Solid-phase extraction

^(64)Cu radiolabeled nanomaterials for positron emission tomography(PET)imaging被引量：3: 《Chinese Chemical Letters》2022年第7期3349-3360,共12页Xueqian Chen Wenchao Niu Zhongying Du Yong Zhang Dongdong Su Xueyun Gao; supported by the National Natural Science Foundation of China(Nos.U2067214,21727817);Beijing municipal education commission-Beijing natural science foundation joint funding project(No.KZ202010005006)。; The prevalence of positron emission tomography(PET)imaging has advanced biomedical applications for its ultrahigh sensitivity,deep tissue penetration and quantitative visualization of diseases in vivo.^(64)Cu with ide...; 关键词：^(64)Cu Positron emission tomography Chelating agent-free Radiolabeling strategies Imaging guided therapy

Natural product-based radiopharmaceuticals:Focus on curcumin and its analogs,flavonoids,and marine peptides: 《Journal of Pharmaceutical Analysis》2022年第3期380-393,共14页Hendris Wongso; Natural products provide a bountiful supply of pharmacologically relevant precursors for the development of various drug-related molecules,including radiopharmaceuticals.However,current knowledge regarding the importa...; 关键词：Natural products RADIOPHARMACEUTICALS RADIOLABELING CURCUMIN FLAVONOIDS Marine peptides

An efficient method for the site-specific ^(99m)Tc labeling of nanobody: 《Biophysics Reports》2021年第4期295-303,共9页Qi Luo Hannan Gao Jiyun Shi Fan Wang; This work was supported by National Natural Science Foundation of China(81630045,81927802 and 81971676);and Emergency Key Program of Guangzhou Laboratory(EKPG21-16).; Recently,there has been a lot of interest by using nanobodies(heavy chain-only antibodies produced naturally from the Camelidae)as targeting molecules for molecular imaging,especially for the nuclear medicine imaging....; 关键词：NANOBODY Sortase A Site-specific radiolabeling ^(99m)Tc

Radiosynthesis of [^(18)F]ArylSCF2H Using Aryl Boronic Acids, S-(Chlorofluoromethyl) benzenesulfonothioate and [^(18)F]Fluoride: 《CCS Chemistry》2021年第7期1921-1928,共8页Qunchao Zhao Patrick G.Isenegger Thomas C.Wilson Jeroen BISap Florian Guibbal Long Lu Véronique Gouverneur Qilong Shen; support from National Natural Science Foundation of China(nos.21625206,21632009,and 21421002);the Strategic Priority Research Program of the Chinese Academy of Sciences(no.XDB20000000);the Engineering and Physical Sciences Research Council(nos.EP/NP509711/1,EP/L025604/1,and NS/A000024/1);the Biotechnology and Biological Sciences Research Council(no.BB/P026311/1),Pfizer,the Swiss National Science Foundation(no.P2BSP2_178609),and Cancer Research UK(no.C5255/A16466).; Herein,we report a mild and practical protocol for the copper-catalyzed chlorofluoromethylthiolation of(hetero)aryl boronic acids with the novel reagent PhSO2SCFClH.The resulting products are amenable to halogen-excha...; 关键词：chlorofluoromethylthiolation boron reagent PET FLUORINE RADIOLABELING

Radiolabeling of lacosamide using highly purified rhenium-188 as a prospective brain theranostic agent被引量：1: 《Nuclear Science and Techniques》2020年第10期105-114,共10页H.A.El-Sabagh M.I.Aydia A.M.Amin K.M.El-Azony; Rhenium-188 is prospectively effective for both diagnosis and radiotherapy as it appropriately emits gamma rays and beta particles.Lacosamide(LCM)is a newly approved antiepileptic medication for focal drug-resistant e...; 关键词：LACOSAMIDE 188Re 188W/188Re generator RADIOLABELING

Radiolabeling, docking studies, in silico ADME and biological evaluation of serotonin with 125I for 5-HTRs imaging: 《Nuclear Science and Techniques》2020年第8期64-71,共8页Dina M.El-Sharawy Marwa S.El Refaye H.Hussien Asmaa M.AboulMagd; Serotonin is one of the significant signaling molecules used by several neural systems in the gut and brain. This study aimed to develop a novel and potent tracer for targeting, detecting, and imaging serotonin recept...; 关键词：SEROTONIN Electrophilic substitution Molecular modeling 5HTRs

General synthesis of silica-based yolk/shell hybrid nanomaterials and in vivo tumor vasculature targeting: 《Nano Research》2018年第9期4890-4904,共15页Feng Chen Shreya Goel Sixiang Shi Todd E. Barnhart Xiaoli Lan Weibo Cai; Multifunctional yolk/shell-structured hybrid nanomaterials have attracted increasing interest as theranostic nanoplatforms for cancer imaging and therapy. However, because of the lack of suitable surface engineering a...; 关键词：yolk/shelLintrinsic radiolabeling vasculature targeting positron emission tomography zirconium-89

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