LACOSAMIDE

作品数：6被引量：6H指数：2
导出分析报告
相关领域：医药卫生更多>>
相关期刊：《Chemical Research in Chinese Universities》《中华医学信息导报》《国外药讯》《Science China Chemistry》更多>>
相关基金：国家自然科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-6
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Unraveling the neuroprotective effect of perampanel and lacosamide combination in the corneal kindling model for epilepsy in mice
《Animal Models and Experimental Medicine》2025年第2期222-238,共17页Saba Tehreem Azka Sabir Maryam Farooq Waseem Ashraf Faleh Alqahtani Tanveer Ahmad Imran Imran 
The authors extended their appreciation to Distinguished Scientist Fellowship program at King Saud University,Riyadh,Saudi Arabia,for funding this work through research supporting project number(RSP2024R131).
Background:Scientific evidence to guide clinicians on the use of different antiseizure drugs in combination therapy is either very limited or lacking.In this study,the impact of lacosamide and perampanel alone and in ...
关键词：behavioral studies corneal kindling LACOSAMIDE learned helplessness oxidative stress PERAMPANEL 
Radiolabeling of lacosamide using highly purified rhenium-188 as a prospective brain theranostic agent被引量：1
《Nuclear Science and Techniques》2020年第10期105-114,共10页H.A.El-Sabagh M.I.Aydia A.M.Amin K.M.El-Azony 
Rhenium-188 is prospectively effective for both diagnosis and radiotherapy as it appropriately emits gamma rays and beta particles.Lacosamide(LCM)is a newly approved antiepileptic medication for focal drug-resistant e...
关键词：LACOSAMIDE 188Re 188W/188Re generator RADIOLABELING 
Enantioselective three-component Ugi reaction catalyzed by chiral phosphoric acid被引量：3
《Science China Chemistry》2020年第1期47-54,共8页Jian Zhang Yi-Yan Wang He Sun Shao-Yu Li Shao-Hua Xiang Bin Tan 
supported by the National Natural Science Foundation of China(21825105,21772081);Shenzhen Special Funds for the Development of Biomedicine,Internet,New Energy and New Material Industries(JCYJ20170412151701379,KQJSCX20170328153203);Special Funds for the Cultivation of Guangdong College Students’ Scientific and Technological Innovation(PDJH2019C467)
A catalytic enantioselective three-component Ugi reaction was developed.SPINOL-derived phosphoric acid with bulky 2,4,6-tricyclohexylphenyl groups at the 6,6′positions was found to be the best catalyst to affordα-am...
关键词：α-amino amide Ugi reaction chiral phosphoric acid ENANTIOSELECTIVITY LACOSAMIDE 
Improved Method for Lacosamide Synthesis with Chemoenzymatic Method
《Chemical Research in Chinese Universities》2012年第5期833-836,共4页WANG Zhi-yuan XU Li-sheng LIU Jun-zhong ZHANG Hong-juan GAO Ji LIU Qian JIAO Qing-cai 
Supported by the National Technology-Innovation Fund(No.02CJ-13-01-16);the Open Fund of State Key Laboratory of Pharmaceutical Biotechnology of Nanjing University, China
Lacosamide was prepared by chemical method coupled with enzymatic method. N-Acetyl-D, L-3-methoxy-alanine, derived from D,L-3-methoxy-alanine, was used in the resolution process catalyzed by immobilized Escherichia co...
关键词：LACOSAMIDE AMINOACYLASE N-Acetyl-D L-3-methoxy-alanine Immobilized cell 
lacosamide作为辅助治疗可明显减少部分性癫痫发作
《中华医学信息导报》2009年第5期10-10,共1页王敏（摘译） 
一项涉及难治性部分性癫痫发作的3期研究显示：新药lacosamide作为辅助治疗可显著降低癫痫发作频率，且耐受性良好。
关键词：部分性癫痫发作 辅助治疗 发作频率 难治性 耐受性 
Lacosamide可减少惊厥14．4％被引量：2
《国外药讯》2007年第7期18-19,共2页范丽珠（摘） 
在美国加州圣地亚哥举行的北美地区癫痫会议上，德国Schwarz Pharma公司宣读了其口服lacosamide（Ⅰ）作为成人未控制的部分性惊厥的辅助治疗的Ⅲ期试验中安全性和疗效的阳性资料。（Ⅰ）200mg／日和（Ⅰ）400mg／日两组都显示比安慰剂...
关键词：惊厥 Pharma公司 抗癫痫药 北美地区 阳性资料 Ⅲ期试验 辅助治疗 安全性 
全选清除导出
共1页<1>
检索报告 对象比较 聚类工具 使用帮助 返回顶部