云南高校图书馆联盟文献共享服务平台- AMINOACYLASE

AMINOACYLASE: 作品数：24被引量：6H指数：1; 导出分析报告; 相关领域：生物学理学更多>>; 相关作者：李莉莉李晓敏宋正孝李牧彭英更多>>; 相关机构：长春理工大学天津大学更多>>; 相关期刊：《Chemical Research in Chinese Universities》《Chinese Journal of Reactive Polymers》《Acta Pharmacologica Sinica》《Science China Chemistry》更多>>; 相关基金：国家自然科学基金天津市自然科学基金中国博士后科学基金浙江省自然科学基金更多>>

Aminoacylase-1 plays a key role in myocardial fibrosis and the therapeutic effects of 20(S)-ginsenoside Rg3 in mouse heart failure被引量：1: 《Acta Pharmacologica Sinica》2022年第8期2003-2015,共13页Qiong Lai Fu-ming Liu Wang-lin Rao Guang-ying Yuan Zhao-yang Fan Lu Zhang Fei Fu Jun-ping Kou Bo-yang Yu Fang Li; supported by the National Natural Science Foundation of China(81774150,81973506,82104437);Natural Science Foundation of Jiangsu Province(BK20210431);China Postdoctoral Science Foundation(2021M693519);National Innovation and Entrepreneurship Training Program for Undergraduate(202110316013Y);“Double First-Class”University project(CPU2018GF06,CPU2018GF07).; We previously found that the levels of metabolite N-acetylglutamine were significantly increased in urine samples of patients with heart failure(HF)and in coronary artery ligation(CAL)-induced HF mice,whereas the expr...; 关键词：heart failure myocardial fibrosis N-acetylglutamine aminoacylase-1 20(S)-ginsenoside Rg3 targeted metabolomics analysis

Improved Method for Lacosamide Synthesis with Chemoenzymatic Method: 《Chemical Research in Chinese Universities》2012年第5期833-836,共4页WANG Zhi-yuan XU Li-sheng LIU Jun-zhong ZHANG Hong-juan GAO Ji LIU Qian JIAO Qing-cai; Supported by the National Technology-Innovation Fund(No.02CJ-13-01-16);the Open Fund of State Key Laboratory of Pharmaceutical Biotechnology of Nanjing University, China; Lacosamide was prepared by chemical method coupled with enzymatic method. N-Acetyl-D, L-3-methoxy-alanine, derived from D,L-3-methoxy-alanine, was used in the resolution process catalyzed by immobilized Escherichia co...; 关键词：LACOSAMIDE AMINOACYLASE N-Acetyl-D L-3-methoxy-alanine Immobilized cell

Enantioselective synthesis of L-homophenylalanine by whole cells of recombinant Escherichia coli expressing L-aminoacylase and N-acylamino acid racemase genes from Deinococcus radiodurans BCRC12827: 《中国生物学文摘》2007年第3期9-9,共1页Hsu, S. K. Lo, H. H. Kao, C. H. Lee, D. S. Hsu, W. H.; 关键词：L-酰化氨基酸水解酶 N-酰基氨基酸血管紧张素转换酶抑制剂痴呆药物合成

Immobilization of Aspergillus Oryzae Mycelium Pellets and Its Application in the Resolution of D, L-Alanine: 《Transactions of Tianjin University》2006年第4期242-247,共6页王燕朱怀工张凤宝王淑兰蔡旺锋张旭斌; Aspergillus oryzae 3042 mycelium pellets were immobilized by crosslinking method with reagents of gelatin and formaldehyde. An orthogonal design table was used to determine the optimal immobilization conditions. The L...; 关键词：L-aminoacylase Aspergillus oryzae IMMOBILIZATION CROSSLINKING ALANINE pHi temperature

Low Temperature Induced Conformation Changes of Aminoacylase: 《Tsinghua Science and Technology》2004年第1期76-80,共5页谢强孟凡国周海梦; the National Key Basic Research and Development (973) Program of China (No. G1999075607); Control of aggregation, by lowering temperature and protein concentrations, can enhance the extent of successful refolding. The low temperature has been used in protein folding studies, as undesired aggregations often...; 关键词：low temperature AMINOACYLASE secondary structure

Enhancement of Aminoacylase Activity by Sodium Citrate: 《Tsinghua Science and Technology》2001年第5期421-425,共5页于范利曹志方李森周海梦; Kidney and other tissues of animals and humans have a high concentration of citrate which is an important intermediate substance in the citrate cycle. Citrate may play an important physiological role in metabolism. ...; 关键词：AMINOACYLASE sodium citrate ACTIVATION DENATURATION UNFOLDING

Cause of Irreversible Inactivation of Aminoacylase in Urea Solution: 《Tsinghua Science and Technology》1999年第3期1528-1531,共4页杨弋周海梦; Some have suggested that the refolding of denatured aminoacylase is difficult. The present study reports that aminoacylase denatured in urea concentrations more than 4?mol/L was markedly but partially unfolded and cou...; 关键词：AMINOACYLASE UNFOLDING REFOLDING REACTIVATION UREA

Surface Modification of Silica Gels as Carrier for AminoacylaseImmobilization: 《Chinese Chemical Letters》1998年第2期161-163,共3页Liu, LJ Qiu, GS Zhuo, RX Pan, ZT; The surface of silica gels was modified by an diethylamino group and an hydroxy group, simultaneously. The activity of the aminoacylase immobilized on such amino-hydroxy-silica gels was 316.8 U/g. By its catalysis, th...; 关键词：immobilized aminoacylase silica gels surface modification RESOLUTION amino acid

Crystallization and preliminary X-ray studies of porcine kidney aminoacylase Ⅰ被引量：1: 《Chinese Science Bulletin》1997年第20期1750-1752,共3页ZHAOHaiyan, MENGWuyi, LIN Zhengjiong and ZHOU Haimeng1. National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China 2. Department of Biological Science and Biotechnology, Tsinghua University, Beijing 100084, China; AMINOACYLASE Ⅰ（ACY-1）（E. C. 3. 5. 1. 14 ） participated in amino acid metabolism existingin mammalian kidney and microorganisms, and catalyzes reversible hydrolysis of acylaminoacids. ACY-1 consists of 772 amino ...; 关键词：AMINOACYLASE I CRYSTALLIZATION PRELIMINARY crystallography.

IMMOBILIZED ASPERGILLUS ORYZAE CELLS AND THEIR ACTIVITIES: 《Transactions of Tianjin University》1997年第2期14-18,共5页宋正孝李晓敏王诤彭英; Aminoacylase was immobilized on the mycelium cells of Aspergillus oryzae by using ethylenediamine, gelatin and glutylalhyde. The proper immobilized condition was studied by orthogonal experimental design. The immo...; 关键词：IMMOBILIZATION ASPERGILLUS AMINOACYLASE optically resolution

AMINOACYLASE