FLUORINE-18

作品数：27被引量：37H指数：4
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Synthesis and evaluation of TSPO-targeting radioligand[^(18)F]F-TFQC for PET neuroimaging in epileptic rats
《Acta Pharmaceutica Sinica B》2025年第2期722-736,共15页Wenhui Fu Qingyu Lin Zhequan Fu Tingting Yang Dai Shi Pengcheng Ma Hongxing Su Yunze Wang Guobing Liu Jing Ding Hongcheng Shi Dengfeng Cheng 
supported by the National Natural Science Foundation of China(No.82172002 and 82272058,China);Shanghai Municipal Science and Technology Committee of Shanghai Outstanding Academic Leaders Plan(No.21XD1423500,China);National Key Research and Development Program of China(No.2022YFC2406901).
The translocator protein(TSPO)positron emission tomography(PET)can noninvasively detect neuroinflammation associated with epileptogenesis and epilepsy.This study explored the role of the TSPO-targeting radioligand[^(1...
关键词：FLUORINE-18 TSPO PET Epilepsy NEUROIMAGING 
Recent advances in photochemistry for positron emission tomography imaging被引量：1
《Chinese Chemical Letters》2024年第8期149-162,共14页Jing-Jing Zhang Lujun Lou Rui Lv Jiahui Chen Yinlong Li Guangwei Wu Lingchao Cai Steven H.Liang Zhen Chen 
the financial support from the Basic Research Program of Jiangsu Province(No.BK20220408).
As a powerful noninvasive imaging technology,positron emission tomography(PET)has been playing an important role in disease theranostics and drug discovery.The successful application of PET relies on not only the biol...
关键词：Positron emission tomography(PET) FLUORINE-18 Carbon-11 PHOTOCATALYSIS AUTOMATION Late-stage functionalization 
Significance of incidental focal fluorine-18 fluorodeoxyglucose uptake in colon/rectum,thyroid,and prostate:With a brief literature review
《World Journal of Clinical Cases》2022年第34期12532-12542,共11页Haejun Lee Kyung-Hoon Hwang 
BACKGROUND Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography(F-18 FDG PET/CT),a functional imaging method,is usually performed on the entire torso,and regions of unexpected suspicious foc...
关键词：INCIDENTAL FOCAL Uptake Fluorine-18 fluorodeoxyglucose Positron emission tomography/computed tomography Standardized uptake value 
Peptides Radiofluorination: Main Methods and Highlights
《International Journal of Organic Chemistry》2022年第4期161-172,共12页Ana Carolina A. Bispo Fernanda A. F. Almeida Juliana B. Silva Marcelo Mamede 
Peptides have an important role in organism and its high quantity present in tumors leading to development of radiolabeled peptides for tumor-specific imaging. Once the traditional methodologies used for radiofluorina...
关键词：RADIOFLUORINATION RADIOLABELING PEPTIDES Prosthetic Groups FLUORINE-18 
A novel monoacylglycerol lipase-targeted^(18)F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network
《Acta Pharmacologica Sinica》2022年第11期3002-3010,共9页Ran Cheng Masayuki Fujinaga Jing Yang Jian Rong Ahmed Haider Daisuke Ogasawara Richard S.Van Tuo Shao Zhen Chen Xiaofei Zhang Erick R.Calderon Leon Yiding Zhang Wakana Mori Katsushi Kumata Tomoteru Yamasaki Lin Xie Shaofa Sun Lu Wang Chongzhao Ran Yihan Shao Benjamin Cravatt Lee Josephson Ming-Rong Zhang Steven H.Liang 
the National Natural Science Foundation of China(No.81801770);the Natural Science Foundation of Tianjin City(19JCQNJC11100).
Monoacylglycerol lipase(MAGL)constitutes a serine hydrolase that orchestrates endocannabinoid homeostasis and exerts its function by catalyzing the degradation of 2-arachidonoylglycerol(2-AG)to arachidonic acid(AA).As...
关键词：monoacylglycerol lipase(MAGL) positron emission tomography(PET) diagnostic imaging FLUORINE-18 brown adipose tissue(BAT) 
Synthesis and characterization of the two enantiomers of a chiral sigma-1 receptor radioligand:(S)-(+)-and(R)-(-)-[^(18)F]FBFP
《Chinese Chemical Letters》2022年第7期3543-3548,共6页Tao Wang Ying Zhang Xiaojun Zhang Leyuan Chen Mingqiang Zheng Jinming Zhang Peter Brust Winnie Deuther-Conrad Yiyun Huang Hongmei Jia 
the financial support from Beijing Natural Science Foundation(No.7212203);National Natural Science Foundation of China(No.21876013)。
Racemic[^(18)F]FBFP([^(18)F]1)proved to be a potentσ_(1) receptor radiotracer with superior imaging properties.The pure enantiomers of unlabeled compounds(S)-and(R)-1 and the corresponding iodonium ylide precursors w...
关键词：σ_(1)receptor ENANTIOMER Radiotracer Positron emission tomography FLUORINE-18 
Assessment of incidental focal colorectal uptake by analysis of fluorine-18 fluorodeoxyglucose positron emission tomography parameters
《World Journal of Clinical Cases》2022年第17期5634-5645,共12页Haejun Lee Kyung-Hoon Hwang Kwang An Kwon 
BACKGROUND Colon and rectal cancers are among the top five cancers worldwide in terms of their incidence and mortality rates.As the treatment options for cure include surgery even in specific advanced-stage cases,the ...
关键词：COLORECTAL INCIDENTAL Fluorine-18 fluorodeoxyglucose Positron emission tomography/computed tomography Standardized uptake value 
Is there utility for fluorine-18-fluorodeoxyglucose positron-emission tomography scan before surgery in breast cancer? A 15-year overall survival analysis
《World Journal of Clinical Oncology》2022年第4期287-302,共16页Justine Perrin Karim Farid Hilde Van Parijs Olena Gorobets Vincent Vinh-Hung Nam P Nguyen Navid Djassemi Mark De Ridder Hendrik Everaert 
BACKGROUND The prognostic value of preoperative fluorine-18-fluorodeoxyglucose positronemission tomography(18 F-FDG PET)scan for determining overall survival(OS)in breast cancer(BC)patients is controversial.AIM To eva...
关键词：Restricted mean survival time Long-term prognosis Overall survival Preoperative workup Breast surgery Positron-emission tomography scan 
Discovery and development of brain-penetrant ^(18)F-labeled radioligands for neuroimaging of the sigma-2 receptors
《Acta Pharmaceutica Sinica B》2022年第3期1406-1415,共10页Ying Zhang Tao Wang Xiaojun Zhang Winnie Deuther-Conrad Hualong Fu Mengchao Cui Jinming Zhang Peter Brust Yiyun Huang Hongmei Jia 
supported by the National Natural Science Foundation of China(No.21876013);Beijing Natural Science Foundation(7212203,China)。
We have discovered and synthesized a series of indole-based derivatives as novel sigma-2(σ_(2))receptor ligands.Two ligands with high σ_(2) receptor affinity and subtype selectivity were then radiolabeled with F-18 ...
关键词：Indole-based derivatives σ2 receptor FLUORINE-18 Positron emission tomography NEUROIMAGING 
The Role of <sup>18</sup>F-FDG PET/CT in Staging Breast Carcinoma in Hanoi Oncology Hospital, Vietnam
《Journal of Biosciences and Medicines》2022年第1期190-201,共12页Cuong Duy Dang Thang Van Nguyen Tuynh Van Chu Huy Quang Pham 
Purpose: This study aimed to evaluate the role of 18F-FDG PET/CT scans in staging breast carcinoma. Materials and Methods: A descriptive study on 46 patients who were diagn...
关键词：18F-FDG PET/CT (Positron Emission Tomography with 2-Deoxy-2-[Fluorine-18]Fluoro-D-Glucose Integrated with Computed Tomography) Breast Carcinoma STAGING SUV (Standardized Uptake Value) 
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