ENANTIOMER

作品数：61被引量：96H指数：4
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相关领域：理学更多>>
相关作者：邓芳更多>>
相关机构：湖南师范大学更多>>
相关期刊：《Emerging Contaminants》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Science China Chemistry》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金更多>>
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A new green approach to synthesizing MIP-202@porous silica microspheres for positional isomer/enantiomer/hydrophilic separation
《Chinese Chemical Letters》2025年第1期501-505,共5页Zhefei Hu Jingwen Liao Jiawen Zhou Lulu Zhao Yanjuan Liu Yuefei Zhang Wei Chen Sheng Tang 
support of National Natural Science Foundation of China(No.21906124);Natural Science Foundation of Hubei Province(No.2017CFB220)。
Metal-organic frameworks(MOFs)with superior physicochemical properties have great potential for applications in chromatographic separation.However,currently popular methods for the synthesis of MOFbased silica composi...
关键词：Metal-organic framework Stationary phase Deep eutectic solvent Green chromatography High-performance liquid chromatography 
Tetraphenylethylene dicycle helicates: circularly polarized luminescence and chiral recognition based on emission wavelength change
《Science China Chemistry》2024年第11期3817-3824,共8页Zhi-Rong Xu Miao-Li Gao Ming Hu Wei Yu Yan-Song Zheng 
the National Natural Science Foundation of China (22072050 and 22372066) for financial support。
Chiral tetraphenylethylene(TPE) dicycle tetraaldehyde and TPE dicycle tetraacids bearing optically pure groups on the cycles were designed and synthesized. Due to the propeller-like conformation immobilization of TPE ...
关键词：TPE dicycle helicate CPL chiral recognition enantiomer excess analysis emission wavelength change 
Aldehyde oxidase mediated enantioselective metabolic health risk of dinotefuran
《Science China Chemistry》2024年第6期2079-2091,共13页Liwei Xu Xinxin Xu Hua Kuang Chuanlai Xu Xiaoling Wu 
supported by the National Natural Science Foundation of China(22276076,22306074,22361132536,22236002);the Fundamental Research Funds for the Central Universities(JUSRP622032);the Jiangsu Association for Science and Technology Youth Science and Technology Talent Support Project(TJ2021-049)。
Chiral pollutants often pose significant differential environmental health risks.In this study,the biotransformation of chiral dinotefuran(DIN)and its enantioselective metabolic toxicity mechanisms have been systemica...
关键词：neonicotinoid dinotefuran ENANTIOMER aldehyde oxidase metabolomics health risk 
Chiral drugs:Sources,absolute configuration identification,pharmacological applications,and future research trends
《LabMed Discovery》2024年第1期40-48,共9页Shou-jiao Peng Yu-ying Zhu Chun-ying Luo Pei Zhang Fei-yun Wang Rui-xiang Li Guo-qiang Lin Jian-ge Zhang 
supported by the Shanghai Science and Technology Development Fund from the Central Leading Local Government(No.YDZX20223100001004);the Organizational Key Research and Development Program of SHUTCM(No.2023YZZ01);the Shanghai Pujiang Program(No.23PJ1411200).
Chirality is one of the essential attributes of nature.Chiral drugs refer to a class of drugs containing chiral centers,and the molecular stereo-structures of their enantiomers are non-superimposable mirror images of ...
关键词：Chiral drug ENANTIOMER Traditional Chinese medicine(TCM) Pharmacological application 
Integrated separation-electrochemical detection device based on wood column for online identification of enantiomer
《Nano Research》2024年第3期1893-1901,共9页Junli Guo Yuanfei Xue Chenxi Zhao Junjian Zhao Zhida Gao Ye Mei Yan-Yan Song 
supported by the National Natural Science Foundation of China(Nos.22074013 and 22073030);The CPU time was supported by the Supercomputer Centre of East China Normal University(ECNU Public Platform for Innovation No.001).
Chiral chemicals have attracted significant interest in the pharmaceutical industry,yet the separation methods to get pure enantiomers from racemic mixture are still challenging.To date,the separation of enantiomers s...
关键词：wood column integrated separation-detection device ENANTIOSELECTIVITY online sensing free energy barrier 
Frequency selective fingerprint sensor:the Terahertz unity platform for broadband chiral enantiomers multiplexed signals and narrowband molecular AIT enhancement被引量：2
《PhotoniX》2023年第1期188-201,共14页Jiaming Lyu Shengyuan Shen Lin Chen Yiming Zhu Songlin Zhuang 
Basic Science Center Project of the National Natural Science Foundation of China[Grant No.61988102];National Natural Science Foundation of China[Grant No.62275157];Shanghai Shuguang Program[Grant No.18SG44];111 Project[Grant No.D18014].
Chiral enantiomers have different pharmacological and pharmacokinetic characteristics. It is important to strictly detect chiral component for avoiding being harmful to the human body due to side effects. Terahertz (T...
关键词：Chiral enantiomer Frequency-selective fingerprint sensor Multiplexing Absorption induced transparency Fingerprints identification 
(+)-Borneol enantiomer ameliorates epileptic seizure via decreasing the excitability of glutamatergic transmission被引量：3
《Acta Pharmacologica Sinica》2023年第8期1600-1611,共12页Yu Wang Xiao-yun Qiu Jia-ying Liu Bei Tan Fei Wang Min-juan Sun Xu-hong Jiang Xu-ming Ji Ceng-lin Xu Yi Wang Zhong Chen 
supported by grants from the National Key R&D Program of China (2021ZD0202803 and 2020YFA0803902);the National Natural Science Foundation of China (82022071);the Natural Science Foundation of Zhejiang Province (LD22H310003);the Research Project of Zhejiang Chinese Medical University (2022JKJNTZ13).
Epilepsy is one common brain disorder,which is not well controlled by current pharmacotherapy.In this study we characterized the therapeutic potential of borneol,a plant-derived bicyclic monoterpene compound,in the tr...
关键词：epilepsy anti-seizure drug (+)-borneol valproate SUBICULUM glutamatergic synaptic transmission 
Synthesis and characterization of the two enantiomers of a chiral sigma-1 receptor radioligand:(S)-(+)-and(R)-(-)-[^(18)F]FBFP
《Chinese Chemical Letters》2022年第7期3543-3548,共6页Tao Wang Ying Zhang Xiaojun Zhang Leyuan Chen Mingqiang Zheng Jinming Zhang Peter Brust Winnie Deuther-Conrad Yiyun Huang Hongmei Jia 
the financial support from Beijing Natural Science Foundation(No.7212203);National Natural Science Foundation of China(No.21876013)。
Racemic[^(18)F]FBFP([^(18)F]1)proved to be a potentσ_(1) receptor radiotracer with superior imaging properties.The pure enantiomers of unlabeled compounds(S)-and(R)-1 and the corresponding iodonium ylide precursors w...
关键词：σ_(1)receptor ENANTIOMER Radiotracer Positron emission tomography FLUORINE-18 
Molecular self-induced configuration for improving dissymmetry factors in tetradentate platinum(Ⅱ) enantiomers cycloaddition被引量：1
《Chinese Chemical Letters》2022年第3期1459-1462,共4页Li Yuan Qian-Jun Ding Zhen-Long Tu Xiang-Ji Liao Xu-Feng Luo Zhi-Ping Yan Zheng-Guang Wu You-Xuan Zheng 
supported by the National Natural Science Foundation of China (Nos. 51773088 and 21975119)。
Two pairs of Pt(Ⅱ) enantiomers((RR)/(SS)-Py Pt,((RR)/(SS)-Py: N,N’-(1,2-diphenylethane-1,2-diyl)dipicolinamide;(RR)-P/M-QPt,((RR)/(SS)-Q: N,N’-((1R,2R)-1,2-diphenylethane-1,2-diyl)bis(quinoline-2-carboxamide)) were...
关键词：Pt(Ⅱ)enantiomer Circularly polarized luminescence Dissymmetry factor Molecular self-induction Helicene-like structure 
Enantiomeric Cephalotaxus alkaloids from seeds of Cephalotaxus oliveri
《Natural Products and Bioprospecting》2022年第1期360-366,共7页Guang-Xing Yu Jing Wu Bao-Bao Shi Mei-Fen Bao Xiang-Hai Cai 
funded in part by the National Natural Science Foundation of China (No.31872677).
Five undescribed alkaloids were isolated from the seeds of Cephalotaxus oliveri along with 27 known ones.The new structures were elucidated based on spectroscopic data including 1D and 2D NMR,MS and calculated ECD spe...
关键词：Cephalotaxus oliveri CEPHALOTAXACEAE ALKALOID ENANTIOMER 
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