EICOSANOIDS

作品数:23被引量:56H指数:4
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相关领域:医药卫生更多>>
相关作者:周晓燕更多>>
相关机构:华中科技大学武汉市中心医院约翰霍普金斯大学南昌大学更多>>
相关期刊:《Journal of Biomedical Research》《Journal of Cancer Metastasis and Treatment》《World Journal of Hepatology》《Food and Nutrition Sciences》更多>>
相关基金:国家自然科学基金更多>>
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Metabolic dysfunction-associated steatotic liver disease and omega- 6 polyunsaturated fatty acids: Friends or foes
《World Journal of Hepatology》2025年第3期180-191,共12页Mona A Hegazy Safaa M Ahmed Shaimaa M Sultan Osama F Afifi Manal A Mohamed Alshimaa E Azab Mohamed A Hassanen Rakan K Zaben 
BACKGROUND Metabolic dysfunction-associated steatotic liver disease(MASLD)is the most common chronic liver disease worldwide.Its prevalence is closely linked to the dramatic rise in obesity and non-communicable diseas...
关键词:Metabolic dysfunction-associated steatotic liver disease Omega-6 polyunsaturated fatty acids Conjugated linoleic acid Arachidonic acid Lipid metabolism Oxidative stress STEATOHEPATITIS EICOSANOIDS 
Morphofunctional characterization of hemocytes in black soldier fly larvae被引量:1
《Insect Science》2023年第4期912-932,共21页Daniele Bruno Aurora Montali Marzia Gariboldi Anna Katarzyna Wronska Agata Kaczmarek Amr Mohamed Ling Tian Morena Casarteli Gianluca Tettamanti 
supported by Fondazione Cariplo(grant number 2020-0900).
In insects,the cell-mediated immune response involves an active role of hemo-cytes in phagocytosis,nodulation,and encapsulation.Although these processes have been well documented in multiple species belonging to diffe...
关键词:EICOSANOIDS encapsulation HEMOCYTES Hermetia illucens immunity PHAGOCYTOSIS 
Hypertrophic Scar Formation and Wound Healing Modulation Fatty Acids as Modulators of Severe Scars
《Modern Plastic Surgery》2023年第1期41-51,共11页Bárbara Díaz Valerie Nuñ ez 
Scar tissue usually generates severe discomfort in the short and long term. Common symptoms include anesthetics sequelae, pruritus, joint malfunction, new wounds on the scar surface, and pain. There are several treatm...
关键词:SCARRING Burn Scar Inflammatory Modulation Cytokine SEQUELAE Fatty Acids EICOSANOIDS Non-Adverse Effects Aesthetics HYPERTROPHIC 
Increased Soluble Epoxide Hydrolase Activity Positively Correlates with Mortality in Heart Failure Patients with Preserved Ejection Fraction:Evidence from Metabolomics被引量:1
《Phenomics》2023年第1期34-49,共16页Liyuan Peng Ziping Song Chengcheng Zhao Kudusi Abuduwufuer Yanwen Wang Zheng Wen Li Ni Chenze Li Ying Yu Yi Zhu Hualiang Jiang Jinshan Shen Xiangrui Jiang Chen Chen Xu Zhang Dao Wen Wang 
supported by grants from the National Natural Science Foundation of China(81790624[to D.W.W.],81900342[to L.P.]and 81790621[to Y.Z.]).
Epoxyeicosatrienoic acids(EETs)have pleiotropic endogenous cardiovascular protective effects and can be hydrolyzed to the corresponding dihydroxyeicosatrienoic acids by soluble epoxide hydrolase(sEH).Heart failure wit...
关键词:Soluble epoxide hydrolase Heart failure with preserved ejection fraction EICOSANOIDS Epoxyeicosatrienoic acids 
Hyperhomocysteinemia dysregulates plasma levels of polyunsaturated fatty acids-derived eicosanoids
《Life Research》2022年第2期32-41,共10页Mohamed Al-Shabrawey Ahmed Elmarakby Yara Samra Mohamed Moustafa Stephen WLooney Krishna Rao Maddipati Amany Tawfik 
supported by1R01EY030054(MA),NIH-1R01EY029751(AT);supported in part by National Center for Research Resources,National Institutes of Health Grant S10RR027926.
Hyperhomocysteinemia(HHcy)contributes to the incidence of many cardiovascular diseases(CVD).Our group have previously established crucial roles of eicosanoids and homocysteine in the incidence of vascular injury in di...
关键词:HOMOCYSTEINE cystathionine β-synthase EICOSANOIDS cycloxygenase LIPOXYGENASE cytochrome-P450 
Deciphering lipid dysregulation in ALS:from mechanisms to translational medicine
《Translational Neurodegeneration》2022年第1期192-218,共27页Ira Agrawal Yong Shan Lim Shi-Yan Ng Shuo-Chien Ling 
National Medical Research Council(NMRC/OFIRG/0042/2017);National Research Foundation(NRF2019-NRF-ISF003-3221);Ministry of Education(MOE-T2EP30220-0029),Singapore to S.-C.L.
Lipids,defined by low solubility in water and high solubility in nonpolar solvents,can be classified into fatty acids,glycerolipids,glycerophospholipids,sphingolipids,and sterols.Lipids not only regulate integrity and...
关键词:Amyotrophic lateral sclerosis SPHINGOLIPIDS TRIGLYCERIDES Phospholipids Cholesterol esters Fatty acids CERAMIDES Arachidonic acid LYSOPHOSPHATIDYLCHOLINE EICOSANOIDS 
A target lipidomics approach to investigate the acute inflammatory irritation induced by indolealkylamines from Chansu water fraction in rats被引量:1
《Chinese Journal of Natural Medicines》2021年第11期856-867,共12页YANG Xin CHEN Wu-Yue GONG Yan DI Liu-Qing DUAN Jin-Ao ZHOU Jing MA Hong-Yue 
This work was supported by the National Natural Science Foundation of China(Nos.82073975,81673563,81102762,and 2018YFC1706200);the Open Project Program of Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization/Jiangsu Key Laboratory for High Technology Research ofTCM Formulae(Nos.ZDXM-1-14,FJGJS-2015-15);the Fund of Quality Standardization of Liu-Shen-Wan(Nos.BA2016104,ZYBZH-C-JS-30),and Jiangsu Qing Lan Project for Young academic leaders.
Chansu has demonstrated adverse reactions in clinical settings,which is associated with its toxicity and limits its clinical applications.But there are methodological limitations for drug safety evaluation.In the curr...
关键词:Chansu Acute inflammatory irritation LIPIDOMICS EICOSANOIDS Molecular docking 
Bioactive lipids and cancer metastasis to bone
《Journal of Cancer Metastasis and Treatment》2021年第1期604-627,共24页Lou Saier Hira Niazi Leyre Brizuela Bodo Levkau Olivier Peyruchaud 
supported by grants from the INSERM(Peyruchaud O),the UniversitéClaude Bernard Lyon 1(Peyruchaud O);and the ANR grant BoneTAX(Grant No.ANR-20-CE14-0036-01)(Peyruchaud O);Saier L was the recipient of a fellowship from the French Ministère de l’Enseignement Supérieur et de la Recherche.Niazi H was supported by Higher Education Commission of Pakistan.This work was funded in part by the Else Kröner-Fresenius-Stiftung(Levkau B).
Bioactive lipids constitute a large family of molecules considered as inflammatory mediators.Among them,lysophosphatidic acid(LPA),sphingosine 1-phosphate(S1P),and eicosanoids(prostanoids such as PGE2 and leukotrienes...
关键词:Lysophosphatidic acid sphingosine 1-phosphate EICOSANOIDS PROSTAGLANDINS LEUKOTRIENES CANCER bone cells 
Endogenous cannabinoids may regulate chronic inflammation in aspirin-exacerbated respiratory disease被引量:1
《World Journal of Otorhinolaryngology-Head and Neck Surgery》2020年第4期255-257,共3页Joshua M.Levy 
The National Center for Advancing Translational Sciences of the National Institutes of Health under Award Number UL1TR002378 and KL2TR002381.The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Aspirin-exacerbated respiratory disease(AERD)is characterized by the triad of chronic rhinosinusitis with nasal polyposis,adult-onset asthma and non-IgE mediated reactions to aspirin and other cyclooxygenase-1(COX-1)i...
关键词:Chronic rhinosinusitis Aspirin-exacerbated respiratory disease Endogenous cannabinoid ENDOCANNABINOIDS EICOSANOIDS PROSTAGLANDINS 
Cytochrome P450 monooxygenase-mediated eicosanoid pathway:A potential mechanistic linkage between dietary fatty acid consumption and colon cancer risk
《Food Science and Human Wellness》2019年第4期337-343,共7页Weicang Wang Jianan Zhang Guodong Zhang 
This research is supported by a new faculty start-up from the University of Massachusetts Amherst,USDA NIFA2016-67017-24423,USDA NIFA 2019-67017-29248,USDA/HatchMAS00492,and NIH/NCIR03 CA218520(to G.Z.).
Human consumption of linoleic acid(LA,18:2ω-6,abundant in vegetable oils)is very high.Animal experiments showed that excessive LA intake increased azoxymethane-induced colon tumorigenesis,however,the impact of excess...
关键词:Linoleic acid Polyunsaturated fatty acids ω-3 Fatty acids Colon cancer Colonic inflammation Cytochrome P450 EICOSANOIDS 
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