BACKGROUND Precision medicine is an emerging field that includes tumor-targeted delivery and tumor microenvironment.This review explores the synergistic potential of combining nano-drug delivery systems with low radia...
the CSIR and DBT for supporting this study;Mizoram University,Aizawl,Mizoram,India,for the MZU-UGC fellowship。
Macrocyclic supramolecular complexes demonstrate the dynamic potential to solve global biomedical challenges,a promising cancer treatment modality.The macrocyclic system is an important heterocyclic system widely pres...
supported by China Postdoctoral Science Foundation(2020M681372);the National Natural Science Foundation of China(Grant Nos.51933002,81902756,82074279);Program of Shanghai Academic Research Leader(20XD1400400);the Natural Science Foundation of Shanghai(20ZR1458300);the Open Project of State Key Laboratory of Molecular Engineering of Polymers(No.K2021-19).
The emergence of multidrug treatment resistance presents a hurdle for the successful chemotherapy of tumours.Ferroptosis,resulting from the iron-dependent accumulation of lipid peroxides,has the potential to reverse m...
Novel biocompatible and brush copolymers have been developed for cancer treatment using its controlled drug-release potential.Polyurethane graft on linear dextrin has been synthesized to control the hydrophilic-hydrop...
We gratefully acknowledge the financial sponsorship of the EPSRC(Grant No.EP/K023845/1);the EPSRC Centre for Doctoral Training in Molecular-Scale Engineering(Grant No.1229421);SDE like to thank the NIHR-HTC for Colorectal Therapies,the MRC-CiC,and the Wellcome Trust ISSF Scheme for financial support.
Lipid and polymer stabilized microbubbles are used in medicine as contrast agents for ultrasound imaging and are being developed for the delivery of water soluble drugs to diseased areas of the body.However,many new t...
This review focuses on organometallic surfactant frameworks considering their wide applications. Organometallic surfactants have grown from being used as dewaxers in complex industrial processes to the production of n...
Supported by The EU"Nano Athero"project FP7-NMP-2012-LARGE-6-309820;the DFG(CI 162/2-1,SPP1681)
Intravascular thrombosis, a critical pathophysiological feature of many cardiovascular disorders, leads to the formation of life-threatening obstructive blood clots within the vessels. Rapid recanalization of occluded...
supported by the National Natural Science Foundations of China (81200924 and 81230027);the Natural Science Foundation of Shanghai Municipality, China (12ZR1427400);the Key Scientific Research Project of Shanghai Municipality, China (11411950300);the Youth Fund of the Shanghai Health Bureau, China (2011);the Innovation Research Program, Second Military Medical University, China (SCMRC1403 and SCMRC1410)
The blood-brain barrier (BBB) maintains homeostasis by blocking toxic molecules from the circulation, but drugs are blocked at the same time. When the dose is increased to enhance the drug concentration in the centr...
supported by the National Natural Science Foundation of China (Nos.21303223 and 311706144).
Photodynamic therapy(PDT)has been a routine treatment of tumors and some microvascular diseases,but clinically available photosensitizers are still scarce.Among all kinds of photo-sensitizers,hypocellins possess the m...
Drug-coated balloon has been developed as an alternative to drug-eluting stents for in-stent restenosis but the performance of drug infusion balloon in such setting has not been previously described. We present a case...