超声造影在射频消融治疗肝转移癌疗效评估的价值  

Value of Contrast-enhanced Ultrasound in Assessment of Curative Effect on Hepatic Metastases Treated with Radiofrequency Ablation

作　　者：芦爱霞[1] 谢玉环[1] 邝永培[1] 林庆陕[1] 马利亚[1] 俞武生[1] 王在国[1] 

机构地区：[1]广东省东莞市人民医院,广东东莞523059

出　　处：《临床医学工程》2012年第3期330-331,共2页Clinical Medicine & Engineering

摘　　要：目的探讨超声造影(contrast-enhanced ultrasound,CEUS)评价射频消融(radiofrequency ablation,RFA)治疗肝脏转移瘤疗效的临床应用价值。方法将31例肝转移瘤病例(共51个病灶)分别行射频消融治疗及超声造影检查;射频消融术前造影观察病灶并制定治疗策略,术后分析病灶造影增强的变化以判断消融效果;病例随访时间为2～22月,术后30min及术后三个月内每月一次、术后3个月后每3个月一次CEUS及增强CT/MRI对照。结果术前超声造影较常规超声多发现病灶8个;治疗后30min46个(46/51,90.2%)病灶动脉期呈无增强区域,5个病灶(5/51,9.8%)动脉期见异常增强信号,即刻行射频消融治疗;随访中4个病灶(4/51,7.8%)见复发。结论超声造影能优化RFA治疗肝脏转移瘤的各个步骤,减少病灶复发,有良好的临床应用前景。Objective To investigate the clinical value of contrast-enhanced ultrasound （CEUS） in the assessment of curative effect on hepatic metastases treated with radiofrequency ablation （RFA）. Methods 31 cases of hepatic metastases （51 lesions） were treated with RFA and examined by CEUS. The lesions were observed through radiography and the strategies of treatment were formulated before RFA; the changes of lesions＇ contrast enhancement after operation were analyzed to evaluate the ablation effect. All cases were followed up for 2 22 months, CEUS and enhanced CT-MRI comparation were taken 30 min after the operation, once every month within three months and once every three months after three months of operation. Results The CEUS found 51 lesions, more than 43 lesions found by conventional ultrasonic. 46 lesions （46/51, 90.2% ） appeared no enhancement in the arterial phase; 5 lesions （5/51, 9.8% ） appeared abnormal enhanced-signal and received the RFA immediately. 4 lesions （4/51,7.8%） had recurrence during follow-up. Conclusions CEUS can optimize the steps of hepatic metastases treated with RFA and decrease the relapse, which has a potential perspective for clinic application.

关 键 词：超声造影 射频消融术 肝转移癌 

分 类 号：R735.7[医药卫生—肿瘤] R814.43[医药卫生—临床医学]