妊娠期乳腺癌临床特点及超声诊断  

Clinical characteristics and ultrasonic diagnosis of breast cancer during pregnancy

作　　者：玄英华[1] 朱庆莉[1] 姜玉新[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院超声诊断科,北京100730

出　　处：《中国医学影像技术》2012年第3期499-502,共4页Chinese Journal of Medical Imaging Technology

基　　金：国家自然科学基金(30970832)

摘　　要：目的探讨妊娠期乳腺癌的临床、超声和病理学特征。方法回顾性分析7例妊娠期诊断为乳腺癌的患者的临床、超声和病理学特征。结果 1例患者在早孕期获得诊断,6例在中晚孕期诊断;对5例行术前超声检查,均表现为形态不规则、边界不清的低回声,其中4例血流丰富,术前均正确诊断为恶性病变;7例患者均接受患侧乳癌改良根治术,孕期未接受化疗及放疗;病理示病灶大小1.7～5.5cm;术后病理5例为浸润性导管癌,1例导管内癌,1例浸润性多形性癌;3例有患侧腋窝淋巴结转移。结论妊娠期乳腺癌恶性度高,预后差,超声有助于早期、正确诊断妊娠期乳腺癌。Objective To investigate clinical findings,ultrasonic and pathological features of breast cancer diagnosed during pregnancy.Methods Clinical data,ultrasonic findings and postoperative pathology of 7 pregnancy patients with breast cancer were analyzed retrospectively.Results One patient was diagnosed in the first trimester while 6 cases were diagnosed in the second and the third trimester.Five of the 7 patients underwent preoperative ultrasonic examinations which showed irregular,ill-defined hypoechoic masses in the breasts with 4 demonstrated rich blood supply indicating malignancy.All cases received modified radical mastectomy,no one underwent chemotherapy and radiation during pregnancy.All the lesions were sized from 1.7 to 5.5 cm.Postoperative pathology showed 5 cases of invasive ductal carcinoma,1 of ductal carcinoma in situ and 1 case of pleomorphic carcinoma.Lymph node involvements were detected in 3 cases.Conclusion Breast cancer during pregnancy is highly malignant and of poor prognosis.Ultrasound assists the early accurate diagnosis of breast cancer during pregnancy.

关 键 词：乳腺肿瘤 妊娠 超声检查 产前 

分 类 号：R739.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]