基于特征配准的[PET＋CT＋MR]“三机三维”影像一体化融合尝试  

Creative 3D-image fusion across 3-module based on characteristic registration in unification

作　　者：彭鳒侨[1] 鞠向阳[2] 李新春[3] 韩佩[4] 朱巧洪[5] 白波[1] 

机构地区：[1]广州医学院第一附属医院关节外科广东省矫形植入骨科重点实验室,广东广州510120 [2]英国格拉斯哥大学牙医学院NHS器械创作部,英国格拉斯哥G23JZ [3]广州医学院第一附属医院关节外科广东省矫形植入骨科重点实验室放射科MR室,广东广州510120 [4]广州医学院第一附属医院关节外科广东省矫形植入骨科重点实验室核医学科PET/CT中心,广东广州510120 [5]广州医学院第一附属医院关节外科广东省矫形植入骨科重点实验室,放射科CT室,广东广州510120

出　　处：《中国医学影像技术》2012年第3期587-591,共5页Chinese Journal of Medical Imaging Technology

基　　金：广东省自然科学基金(S2011010005011);广东省科技厅国际合作攻关引导项目(2011B050400029);广州市教育局立项“十一五”规划教育科学基金(10A074)

摘　　要：目的尝试以基于图像特征的二维图像配准方法,实现PET、MR和CT异机图像之间的精确三维融合。方法输入PET/CT/MR原始数据后,采用数字化格式转换,设计"9点3面"立体定位法进行配准,在Mimics实时工作站按照信息交互自动融合模式并通过信号叠加技术施行图像融合。结果以头、胸、腹为实例交叉试验[CT+MR]、[PET+MR]、[PET+CT]和[PET+CT+MR]立体图像的异机融合,生成了同时分辨软硬组织病灶性质和位置的互补影像。结论在现阶段,此种异机融合方法是对同机成像功用的必要补充。Objective To attempt a registration approach of 2-dimension（2D） image based on image characteristic,in order to accomplish accurate fusion of 3-dimension（3D） from PET,CT and MR images one by one.Methods Digital format was converted after original data of PET/CT/MR input,cubic oriented scheme of ＂9-point and 3-plane＂ for co-registration was designed,and image fusion was implemented at real-time workstation Mimics based on auto-fusing style of information exchanged by signal overlaid technique.Results Cross-modality fusion from cubic images of,,and of patients＇ cranium,chest and abdominal were mutually practiced,complementary images of distinguishing nature and location of lesions between soft and hard tissue were simultaneously created.Conclusion Currently,this sort of multiple modality fusion is an essential complement for the existing function of single modality imaging.

关 键 词：磁共振成像 体层摄影术 X线计算机 正电子发射型体层摄影术 三维重建 特征配准 异机图像融合 

分 类 号：R445[医药卫生—影像医学与核医学]