高阶像差对人工晶状体眼调制传递函数的作用分析  

Effect of higher-order aberration on modulation transfer function in eyes implanted with intraocular lens

作　　者：甄小妹[1] 马忠旭[2] 刘汝瑜[2] 张娜[1] 

机构地区：[1]天津医科大学,天津300070 [2]天津市眼科医院,天津300020

出　　处：《中国实用眼科杂志》2012年第3期250-254,共5页Chinese Journal of Practical Ophthalmology

摘　　要：目的比较两种非球面人工晶状体（intraocular lens，IOL）植入眼6mm瞳孔直径下全眼高阶像差及调制传递函数（modulation transfer function，MTF）值以及不同高阶像差影响下MTF值的变化，分析两组IOL眼MTF值的差异及导致差异的主要高阶像差因素以及影响各组MTF值的主要高阶像差因素。方法临床病例对照研究。对2010年9月至2011年3月在天津眼科医院就诊的病人，选取单纯性老年性白内障患者74例（80只眼），随机分组植入IOL，Ⅰ组AkreosAO；Ⅱ组TecnisZA9003。术后3个月散瞳后行iTrace视功能分析仪测量两组IOL眼6mm瞳孔直径全眼高阶像差、总高阶像差（tHOA）MTF值及分别去除Zernike主要项C3^-3～C3^＋3、C4^0以及不同阶s3、s4、s5后高阶像差的MTF值，独立样本t检验比较两组高阶像差、MTF（tHOA）及去除不同高阶像差后的MTF值，配对样本t检验比较各组内去除不同高阶像差后的MTF值与MTF（tHOA）的差异。结果（1）6mm瞳孔直径，两组全眼球差c4U差异有统计学意义。两组MTF（tHOA）差异有统计学意义，去除C4^0后的MTF值差异无峁寸学意义，分别去除C3^-3～C3^＋3各项后的MTF值差异均有统计学意义。（2）Ⅰ组去除C3^-3～CC3^＋3、C4~后MTF值在（5～30）c／d均有提高，去除c40后MTF值在（5～30）c／d提高最为显著；Ⅱ组去除C3^-3～C3^＋3后MTF值在（5-30）c／d均有提高，去除CO后MTF值在（5-30）c／d无明显变化，去除C／后MTF值在（5～30）c／d提高最为显著。（3）I组去除s3、s4后MTF值在（5～30）c／d均提高，去除s5后MTF值在（5、10）c／d提高，s3、s4对MTF值的影响大于s5。Ⅱ组去除s3后MTF值在（5～30）c／d提高最为显著。结论6mm瞳孔直径下，两组MTF（tHOA）存在差异，球差C4^0是导致差异的主要高阶像差因素；C4^0及s4、s3对AkreosAO IOL眼MTF值影响较大，垂直三叶草c3^-3及S3对Tecnis ZA9003 IOL眼MTF值影响较大。Objective To analyze higher-order aberration, modulation transfer function （MTF） and the changes of MTF value with or without different mode higher-order aberration in eyes implanted with two different types of intraocular lens （IOL） at 6mm pupil diameter. Methods A total of 80 eyes （74 patients） were divided into two groups randomly. Group Ⅰ implanted with Akreos AO IOL, Group Ⅱ implanted with Tecnis ZA9003 IOL. The iTrace was used to measure higher-order ab- errations, MTF value of total higher-order aberration （tHOA）, MTF value without different Zernike （C3^-3- C3^＋3 mode C 3- 3 , C4^0） and different mode of higher-order aberration （S3, S4, S5）. The independent samples t test and paired-t teSt was used to assess the data. Results ①The spherical aberration C4^0 of total eyes was significantly different between the two groups, while the tHOA was not. The MTF value without C4^0 was not significantly different while the MTF （tHOA） and the MTF value without C3-3-C3^＋3 respectively was significantly different between the two groups at 6mm pupil diameter. ②In group, the MTF value improved at （5-30） cycle per degree （c/d） without C-3 C ＋3 3- 3 , C4^0 respectively and the MTF value got the most improvement without C4^0; while in group Ⅱ, the MTF value im-proved at （5-30） c/d without Cf3-C3＋3 respectively and there was no significantly improvement of MTF value without C4^0 at （5-30） c/d, the MTF value got the most improvement without C3^-3. ③In group I, the MTF value improved at （5-30） c/d without S3, S4 respectively and improved at （5- 10） c/d without S5. The MTF value without $3, S4 respectively increased more than without S5; while in group Ⅱ, the MTF value got the most improvement at （5-30） c/d without S3. Conclusions The MTF （tHOA） is different between the two groups, and the spherical aberration C4 is responsible for the difference. C4^0 and S4, S3 show a more significant effect in the eyes implanted with Akreos AO IOL, vertical tr

关 键 词：调制传递函数 高阶像差 人工晶状体 

分 类 号：R776[医药卫生—眼科]