根皮素乙酰阿魏酸酯的合成及抗氧化活性研究  

Synthesis and Antioxidant Activity of Phloretin Acetylferulic Acid Esters

作　　者：李翠苹[1] 余燕影[1] 曹树稳[1,2] 

机构地区：[1]南昌大学化学系,南昌330031 [2]南昌大学食品科学与技术国家重点实验室,南昌330047

出　　处：《天然产物研究与开发》2012年第3期316-320,共5页Natural Product Research and Development

基　　金：国家自然科学基金(20962014)

摘　　要：以阿魏酸和根皮素为原料,合成了三种根皮素乙酰阿魏酸酯,采用IR、1H NMR、13C NMR和HPLC-MS对其结构进行表征。并测定根皮素及其酯的还原能力、清除DPPH自由基及.OH自由基能力,结果表明根皮素乙酰阿魏酸酯的抗氧化活性显著优于根皮素。Three new compounds were firstly synthesized by ferulic acid and phloretin. The target compound was charac- terized by IR,IH NMR,13C NMR and HPLC-MS,respectively. Reducing POwer,DPPH and · OH radical scavenging as- says were carried out to evaluate the antioxidant and free radical scavenging abilities of phloretin and its esters. The re- suits showed that the antioxidant and free radical scavenging abilities of phloretin acetylferulic acid esters were stronger than that of phloretin.

关 键 词：根皮素 阿魏酸 酯化 合成 抗氧化 

分 类 号：O625.32[理学—有机化学]