ERCP下化疗缓释粒子植入胆管治疗中晚期胆管癌疗效评价  

作　　者：姚慧静[1] 

机构地区：[1]山东泰安市中心医院消化内科,271000

出　　处：《中国社区医师（医学专业）》2012年第6期41-41,共1页

摘　　要：目的:初步评价化疗缓释粒子植入治疗中晚期胆管癌的临床疗效及不良反应。方法:选择14例中晚期胆管癌,没有手术指征。ERCP中,在十二指肠镜直视下将5-FU缓释粒子植入到肿瘤部位,每个植入点植入5～6粒缓释粒子,并比较患者症状缓解情况及治疗前后肿瘤大小。结果:全部病例均顺利完成治疗。14例患者中12例在6个月后复查彩超,病灶部分缓解及稳定,再次给予植入治疗,1例在做治疗之前已并发全身广泛转移,病情恶化死亡。结论:ERCP中,在十二指肠镜直视下植入化疗缓释粒子治疗中晚期胆管癌患者,尤其是无法手术者是一种新型的治疗手段,有利于肿瘤局部控制率,是耐受性好的姑息治疗方法。Abstract Objective：To evaluate the clinical efficacy and adverse reactions of sustained - release chemotherapy seed implantation in treatment of bile duct cancer. Mathods ： elect advanced bile duct cancer in 14 cases, there is no indication. ERCP,a colonoscopy under direct vision 5 - FU sustained - release par- ticles into tumor sites, each implanting 5 -6 grain sustained -release implant particle, and compare the symptom relief in patients with tumor size. Results：all the cases are successfully completed treatment. Conclu- sions：it is a new type of treatment that will help local control rate of tumor.

关 键 词：ERCP 化疗 胆管癌 植入 

分 类 号：R735.8[医药卫生—肿瘤]