胃血吸虫病与胃癌的相关性探讨  

Relationship between gastric schistosomiasis and gastric cancer

作　　者：方志恒[1] 王贵和[1] 夏飞[1] 

机构地区：[1]安徽省铜陵市人民医院胃肠外科,244000

出　　处：《中国医师进修杂志》2012年第8期24-25,共2页Chinese Journal of Postgraduates of Medicine

摘　　要：目的探讨胃血吸虫病与胃癌的相关性。方法对11例胃血吸虫病患者的临床资料进行回顾性分析。结果胃血吸虫病并发胃癌的比例为54．5％（6，11），其中高、中分化腺癌占83．3％（5／6）；虫卵沉积处的黏膜有明显肠上皮化生、腺体增生、异型上皮灶及中至重度不典型增生等病理改变。结论胃血吸虫病可显著提高胃癌的发病几率。胃血吸虫病无特征性表现，症状与慢性胃炎酷似。因此，生活于血吸虫病疫区并有类似慢性胃炎的患者，需要增加在胃窦幽门区及小弯侧的活检次数，一旦确诊为胃血吸虫病的患者，要定期接受胃镜检查以监控胃癌的发生。Objective To investigate the relationship between gastric schistosomiasis and gastric cancer. Methods The data of 1 1 cases of gastric schistosomiasis were retrospective analyzed. Results 54.5%（6/11） of gastric schistosomiasis cases complicated with gastric cancer,and 83.3% （5/6） was well-differentiated and moderately differentiated. Seen around the parasite eggs were obvious intestinal metaplasia,gland hyperplasia,ahnormal epithelial lesions and other serious atypical hyperplasia. Conclusions Gastric schistosomiasis significantly increases the risk of gastric cancer. Gastric schistosomiasis does not have specific symptoms,and it is clinically similar to chronic gastritis. Therefore,patients with chronic gastritis-like symptoms in the schistosomiasis endemic areas should be subjected to an intensive test for gastric schistosomiasis in the biopsy specimens collected from pyloric antrum and gastric lesser curvature. Patients infected by gastric schistosomiasis are strongly suggested to go regularly for gastric cancer check with gastroscopy.

关 键 词：胃肿瘤 血吸虫病 

分 类 号：R735.2[医药卫生—肿瘤]