发病时LDL-C/HDL-C数值对脑梗死预后的影响  

Effect of LDL-C/HDL-C on the Prognosis of Cerebral Infarction

作　　者：于红梅[1] 戴其军 柯进[1] 

机构地区：[1]江苏海安县中医院,226600

出　　处：《黑龙江医药》2012年第1期36-37,共2页Heilongjiang Medicine journal

摘　　要：目的:旨在探讨发病时LDL-C/HDL-C数值对脑梗死预后的影响,从而为脑梗死判定预后提供临床指导。方法:⑴82例脑梗死患者入院时均由我院神经专科医师应用mRS及NIHSS量表进行评分,建立卒中登记。入院后第2天检查血脂分析LDL-C/HDL-C数值将其余指标分别分成增高组及正常组,如LDL-C/HDL-C>3为增高组(L1),≤3为正常组(L0)。并且进行mRS、NIHSS评分,分析各个组之间与评分的相关性,对入选人1月及3月后再次进行mRS、NIHSS评分。结果:急性脑梗死入院时,L1组占69.5%,LDL-C/HDL-C比值与mRS及NIHSS评分正相关,且发病1月及3月后两组mRS、NIHSS评分仍有显著性差异(P<0.01)。结论:LDL-C/HDL-C比值越大,发病时病情越严重,预后越差。Objective：To explore the effect of LDL C/HDL C on the prognosis of cerebral infarction,which thereby can provide clinical guidance to the prognosis assessment. Methods：82 cases of cerebral infarction patients admitted to the hospital were classified and scored by neurologist according to mRS and the NIHSS grading standard, and apoplexy registrations were established. All the admission tests, such asLDL- C/HDL -C ,were completed on the 2nd day. The mRS and NIH SS were scored, and relevance scores between various groups were analyzed. Results：If the patients（ L1 ）of the acute cerebral infarction happened at the time of admission, LDL C/HDL C ratio and mRS and NIHSS were positively correlated. 1 month and 3 months after the onset, mRS and NIHSS differed significantly （ P 〈 0. 01 ）. Conclusion： LDL C/HDL C can reflect the comprehensive lipid metabolism level in patients more than a single TC or LDL lipid can do. The larger the LDL C/HDL C ratio at the onset, the more serious the state of the illness will be, which will cause worse prognosis.

关 键 词：脑梗死 预后 LDL-C/HDL-C 

分 类 号：R74[医药卫生—神经病学与精神病学]