孕产妇产前凝血指标和D-二聚体检测分析及临床意义  

Coagulation and D-dimer analysis and clinical significance before motherhood maternity

作　　者：李燕[1] 

机构地区：[1]四川省泸州市人民医院检验科,646000

出　　处：《检验医学与临床》2012年第6期686-686,688,共2页Laboratory Medicine and Clinic

摘　　要：目的探讨凝血酶原时间(PT),活化部分凝血活酶时间(APTT),凝血酶时间(TT),纤维蛋白原(FIB)和D-二聚体(D-D)检测在判断临产孕妇凝血功能状况、出血危险性方面的临床意义。方法采用SysmexCA1500全自动血凝仪对236例住院临产妇和147例健康体检者进行凝血4项和D-D检测并作相关统计分析。结果与健康对照组比较,临产妇组PT、APTT明显降低,FIB和D-D明显增高,差异有统计学意义(P<0.01)。TT无明显变化,与健康对照组比较差异无统计学意义(P>0.05)。结论产前进行凝血4项指标和D-D检测,对预测和治疗产妇异常出血,预防产科意外的发生以及对产程的评估均具有重要的临床参考价值。Objective To explore the clinical significance of prothrombin time（PT）,activated partial thromboplastin time（APTT）,thrombin time（TT）,fibrinogen（FIB） and D-dimer（DD） test in determining the coagulation status of pregnant women in labor,the risk of bleeding.Methods Sysmex CA1500 coagulation analyzer using automatic temporary maternity hospital of 236 cases and 147 healthy subjects for blood clotting 4 and D-dimer,and for related statistical analysis.Results Compared with the healthy control group,PT,APTT significantly reduced clinical maternal group,FIB and DD were significantly increased,the differences were statistically significant（P0.01）.TT had no significant change compared with the control group（P 0.05）.Conclusion Prenatal indicators for coagulation 4 and D-dimer testing can predict and treatment abnormal bleeding,maternal,obstetric accidents prevention and assess production process,which have important clinical reference value.

关 键 词：临产孕妇 凝血酶原时间 活化部分凝血活酶时间 凝血酶时间 纤维蛋白原 D-二聚体 

分 类 号：R743.33[医药卫生—神经病学与精神病学]