Ⅰ级宫颈上皮内瘤变近期随访结果分析  

Analysis on recent follow-up results of cervical intraepithelial neoplasia of Grade Ⅰ

作　　者：池银归[1] 朱珍珍 虞如芬[1] 

机构地区：[1]温州医学院附属第三医院妇产科,浙江瑞安325200 [2]浙江省瑞安市中医院妇产科,浙江瑞安325200

出　　处：《中国现代医生》2012年第10期30-31,共2页China Modern Doctor

基　　金：浙江省瑞安市2011年第二批科技计划项目(201102080)

摘　　要：目的研究Ⅰ级宫颈上皮内瘤变及伴HPV感染者近期自然转归。方法选择符合诊断标准的Ⅰ级宫颈上皮内瘤变并能接受全程(6、12、24个月)随访者439例,分HPV阳性组116例和HPV阴性组323例,观察病变自然转归、HPV感染情况,并进行统计学分析。结果Ⅰ级CIN患者病变和HPV感染均存在双向转归趋势,而HPV阳性者其恶变趋势比阴性者高(P<0.05),HPV感染双向趋势比较差异无统计学意义(P>0.05);HPV阳性者自然愈合率比阴性者低(P<0.05)。结论Ⅰ级CIN患者HPV阳性者可根据情况采取治疗,阴性者可随访观察。Objective To study the natural stage of termination about cervical intraepithelial neoplasia of grade 1 and HIV infected. Methods All of 439 follow-ups （for six, twelve or twenty-four months） of cervical intraepithelial neoplasia of grade I were selected according to a certain diagnostic standard, and were divided into HPV positive group （116 cases） and HPV negative group （323 cases）. The pathological process and HPV infections were observed and analyzed statistically. Results CIN of grade I and HPV exist a two-way stage of termination while HPV positive had a higher malignant change than that of negative （P 〈 0.05）. Comparison of two-way HPV infection had no difference （P 〉 0.05）; The natural healing rate of HPV positive was lower than that of negative （P 〈 0.05）. Conclusion HPV positive with CIN of grade I can take therapeutic schemes according to their conditions and the negative can be evaluated during follow-up period.

关 键 词：宫颈 上皮内瘤变 I级 

分 类 号：R730.1[医药卫生—肿瘤]