生长抑素及凝血酶联合奥美拉唑治疗急性上消化道出血的临床分析  

作　　者：严利桃[1] 

机构地区：[1]四川省成都市第六人民医院,成都610051

出　　处：《北方药学》2012年第3期18-19,共2页Journal of North Pharmacy

摘　　要：目的:观察生长抑素及凝血酶联合奥美拉唑治疗急性上消化道出血的疗效。方法:将32例急性上消化道出血患者随机分成两组,观察组(A)的17例患者持续泵注生长抑素,口服凝血酶及静脉输注奥美拉唑,对照组(B)的15例患者只输注奥美拉唑,观察两组患者出血停止时间。结果:A组17例患者中12例显效(70.6%),2例有效(11.8%),1例无效(6%);B组15例患者中7例显效(46.7%),2例有效(13.3%),6例无效(40%),观察组总有效率显著高于对照组(P<0.01)。结论:生长抑素及凝血酶联合奥美拉唑治疗急性上消化道出血能够明显缩短出血时间,值得临床推广应用。Objective：To investigate the efficacy of somatostatin and thrombin unite omeprazole treatment of acute upper gastrointestinal bleeding. Metheds：32 patients of acute upper gastrointestinal bleeding were randomly divided into two groups, The observation group （A） of 17 patients are given somatostatin treatment by sustained micro-pump ,thrombin peros and intravenous injection of omeprazole,The control group （B）of 15 patients are given only intravenous injection of omeprazole, the bleeding stop time of two groups were observed.Results： In the A group of 17 patients, 12 eases are excellent （70.6%）,2 eases appeared valid （11.8%）, 1 cases are invalid （6%）. In the B group of 15 patients,7 eases are excellent（46.7%）,2 cases appeared valid（13.3%）, 6 cases are？ invalid（40%）,observation group total effectiveness is significantly higher than the control grgup （P〈0.01）.Conelusion ：somatostatln and thrombin unite omeprazole treatment of acute upper gastrointestinal bleeding may shorten Bleeding time obviously,is valuable for clinical popularization.

关 键 词：生长抑素及凝血酶 奥美拉唑 急性上消化道出血 疗效评价 

分 类 号：R573.2[医药卫生—消化系统]