前列地尔联合西洛他唑治疗椎-基底动脉供血不足的临床观察  

Clinical observation on alprostidil and cilostazol in treating vertebral-basilar artery insufficiency

作　　者：王同聚[1] 杨红亚[1] 田松朝[1] 

机构地区：[1]解放军第371中心医院,河南新乡453000

出　　处：《四川医学》2012年第3期459-461,共3页Sichuan Medical Journal

摘　　要：目的探讨前列地尔联合西洛他唑治疗椎-基底动脉供血不足的疗效。方法将84例椎-基底动脉供血不足患者随机分为两组,治疗组42例,对照组42例。对照组给予常规治疗,治疗组在此基础上给予前列地尔加西洛他唑治疗,疗程14d。两组患者治疗前后进行双侧椎动脉和基底动脉的平均血流速度变化监测,治疗后进行疗效评定。结果治疗后治疗组总有效率为90.48%,对照组总有效率为73.80%,治疗组疗效优于对照组(P<0.05);两组治疗后治疗组椎-基底动脉血流速度较对照组明显增高(P<0.05)。结论前列地尔联合西洛他唑治疗椎-基底动脉供血不足的疗效显著,值得临床推广和深入研究。Objective To assess the clinical efficacy of alprostidil and cilostazol in treating vertebral-basilar artery insufficiency.Methods 84 patients with vertebral-basilar artery insufficiency were randomized into two groups： control group in which 42 cases were treated by routine medicine and treatment group in which 42 cases were treated by alprostidil and cilostazol and routine medicine,with a course of 14 days.Effects were evaluated after the treatment,the vertebrobasilar artery blood flow velocity were tested before and after treatment.Results The total effective rate was 90.48% in the treatment group and 73.80% in the control group,with a difference between the two groups（P0.05）;after treatment,the vertebrobasilar artery blood flow velocity of treatment group improved more than those of control group（P0.05）.Conclusion Alprostidil and cilostazol is quite effective against vertebral-basilar artery insufficiency.

关 键 词：椎-基底动脉供血不足 前列地尔 西洛他唑 椎-基底动脉血流速度 

分 类 号：R743[医药卫生—神经病学与精神病学]