112例T_3期喉癌扩大喉部分切除和喉全切除术的疗效分析  

Analysis of curative effect of partial and total laryngectomy on 112 patients with T 3 laryngeal carcinoma

作　　者：杨新明[1] 谢鼎华[1] 贺湘波[1] 

机构地区：[1]长沙湖南医科大学附属第二医院耳鼻咽喉科,410011

出　　处：《耳鼻咽喉（头颈外科）》2000年第1期23-26,共4页Chinese Arch Otolaryngology-Head Neck Surg

摘　　要：目的 :探讨 T3 期扩大喉部分切除和喉全切除术的疗效。方法 :于 1984年 1月至 1996年 5月对 112例 T3 期喉癌的临床资料进行回顾性分析 ,其中行扩大喉部分切除术 4 8例 (单纯手术 2 9例 ,手术加放疗 19例 ) ;喉全切除术 6 4例 (单纯手术 39例 ,手术加放疗法 2 5例 )。结果 :喉部分切除术组和喉全切除术组 3年和 5年生存率分别为 77.1%、6 6 .7%和 97.7%、71.1% ;各组单纯手术和手术加放疗的 3年和 5年生存率比较 ,喉部分切除组分别为 75.7%、6 5.0 %和 78.9%、6 9.2 % ;喉全切除组分别为81.2 %、71.4 %和 76 .0 %、70 .6 % ,各组 3年和 5年生存率均无显著性差异 (P>0 .0 5)。结论 :T3 期喉癌只要掌握好喉部分切除术的适应证 ,其疗效与喉全切除术接近 ;Objective:To evaluate curative effect of partial laryngectomy and total laryngectomy with T 3 laryngeal carcinoma.Methods:One hundred and twelve patients with laryngeal cancer from January 1984 to May 1996 were retrospectively analysed.Partial laryngectomy was conducted in 48 cases (29 with surgery alone,19 with postoperation radiotherapy),total laryngectomy in 64 cases (39 with surgery alone,25 with postoperation radiotherapy).Results:The 3 and 5 years survival rate were 77 1%,66 7% and 79 7% ,71 1% in both groups respectively.The 3 and 5 years survival rate were 75 7%,65 0%and 78 9%,69 2% in patients with partial laryngectomy(without/with radiotherapy),81 2%,71 4% and 76 0%,70 6% with total laryngectomy(without/with radiotherapy)respectively.No significant difference (P>0 05) between the different treatment modalities was found.Conclusions:The result indicated that the curative effect of the partial laryngectomy was close to that of the total laryngectomy with laryngeal carcinoma.Postoperation radiotherapy was unlikely to reduce the risk of local and nodal recurrence. [Chinese Arch Otolaryngol Head Neck Surg,2000;7(1):23~26 From the Department of Otolaryngology,Second Affiliated Hospital of Hunan Medical University,Changsha,410011 (Dr.Yang Xinming)]

关 键 词：喉肿瘤 癌 喉切除术 治疗 

分 类 号：R739.65[医药卫生—肿瘤]