胃癌伴神经内分泌分化的研究现状  

Research status on gastric carcinoma with neuroendocrine differentiation

作　　者：郭思远[1] 张忠涛[1] 孟化[1] 

机构地区：[1]首都医科大学附属北京友谊医院普外科,北京100050

出　　处：《国际外科学杂志》2012年第3期184-188,共5页International Journal of Surgery

基　　金：北京市卫生局青年科学研究资助项目（No.QN2009-004）;国家自然科学基金项目（No.30972887）

摘　　要：胃癌是常见的恶性肿瘤之一，病死率居我国恶性肿瘤首位。而胃又是人体重要的外分泌和内分泌器官，其中一部分胃癌在发生发展过程中就伴随着神经内分泌分化。而至今关于神经内分泌分化还没有明确定义，神经内分泌分化对胃癌患者预后的影响还存在争议，随着对胃癌研究的不断深入，伴神经内分泌分化的胃腺癌的诊断、治疗及预后可能将成为研究热点之一。Gastric cancer is the leading cause of death of patients with malignancy and the most common malignancy in China. Stomach is also a secretory organ, thus the carcinogenesis of human stomach always accompanied neuroendocrine differentiation. There is not a explicit definition of neuroendocrine differentiation so far, and the influence of which in gastric patients prognosis is in dispute. With the deep intensive research of gastric adenocarcinoma, diagnosis and treatment in gastric adenocarcinoma with neuroendocrine differentiation becomes increasingly concerned.

关 键 词：胃癌 神经内分泌分化 神经内分泌肿瘤 混合性腺神经内分泌癌 

分 类 号：R735.2[医药卫生—肿瘤]