肝细胞癌超声造影表现与病理分化程度的研究  

Study on Contrast-enhanced Ultrasonographic Manifestation and Pathological Differentiation of HePatocellular Carcinoma

作　　者：周艳平[1] 廖锦堂[1] 

机构地区：[1]中南大学湘雅医院,湖南长沙410008

出　　处：《医学临床研究》2012年第2期257-259,共3页Journal of Clinical Research

摘　　要：【目的】探讨肝细胞癌（HCC）的超声造影表现与肿瘤病理分化程度的关系。【方法】选择44例HCC患者的44个病灶于外科手术前1周进行超声造影检查（CEUs），分析其时间一强度曲线，得出始增时间、达峰实际、峰值增强时间参数与术后病理分级结果对照。【结果】高、中、低分化HCC组CEUS始增时间分别为（14．72±3．43）S、（15．93±4．08）s、（14．45±2．77）s；达峰时间分别为（31．17土5．89）S、（28．53±8．06）s、（21．54±3．14）S；峰值增强时间分别为（16．44士4．12）s、（12．27士5．6）s、（7．09±1．64）s，不同分化程度HCC的达峰时间、峰值增强时间比较差异有统计学意义（P〈0．05），而始增时间比较差异无统计学意义（P〉0．05）。【结论】超声造影时间一强度曲线可能对肝癌不同分化程度的判断提供一定的参考信息。[Objective] To explore the relationship between contrastenhanced ultrasonographic manifesta tion and tumor pathological differentiation of hepatocellular carcinoma（HCC）. [Methods] Forty four patients （44 lesions） underwent contrastenhanced ultrasound（CEUS） a week before the operation. Timeintensity curve was analyzed. The parameters such as the beginning time of the enhancement, peak time and peak en hancement time were contrasted with the results of pathological grades. [Results]The beginning time of the en hancement in well, moderately and poorly differentiated HCC were （14. 72±3.43）s, （15. 93±4.08）s and （14.45±2.77）s respectively, and the peak time were （31.17±5.89）s, （28.53±8.06）s and （21.54±3.14）s respectively, and the peak enhancement time were （16.44±4.12）s, （12.27±5.6）s and （7.09±1.64）s re spectively. There were significant differences in peak time and peak enhancement time among different degrees of tumor differentiation（ P〈0.05）, but there was no significant difference in the beginning time of the en hancement（ P 〈0.05）. [Conclusion]Timeintensity curve of CEUS may provide some reference information for different degrees of the differentiation of HCC.

关 键 词：超声检查 癌 肝细胞/病理学 

分 类 号：R730.261[医药卫生—肿瘤]