双眼角膜混浊  

Corneal opacity

作　　者：张婷[1] 蒋永祥[1] 徐建江[1] 

机构地区：[1]复旦大学附属眼耳鼻喉科医院眼科,上海200031

出　　处：《中国眼耳鼻喉科杂志》2012年第2期120-122,共3页Chinese Journal of Ophthalmology and Otorhinolaryngology

摘　　要：25岁男性,因"双眼反复红痛、视力下降10余年"入院。双眼最佳矫正视力0.05,裂隙灯检查见双眼角膜浅层基质地图状混浊,余阴性。术前诊断为"双眼Reis-Bücklers角膜营养不良",行左眼角膜板层移植术。病变角膜组织病理检查见Bowmann层及浅基质层散在异常物质,其Masson三重染色,刚果红染色(光镜及偏振光)及PAS染色均阳性。讨论体会:年轻患者双眼角膜混浊应考虑角膜营养不良可能,根据病理和基因检查明确诊断和治疗,如人工泪液、角膜激光切削或者角膜移植。A 25-year-old male was admitted with a 10-year history of recurrent redness, pain, and decrease of visual acuity in both eyes. Best corrective visual acuity was 0.05 bilaterally, and slit lamp examination revealed nothing other than geographic opacity scattered in the superficial stroma of both corneas. Preoperative diagnosis was Reis-Bticklers corneal dystrophy and lamellar keratoplasty was performed in his left eye. Histologic examination revealed abnormal sub- stance both in the Bowmann layer and superficial stroma, which stained with Masson＇ s trichrome, Congo red （under bright and polarized light） and PAS. It must be borne in mind that corneal dystrophy usually manifests in the first decade of life and leads to progressive visual deterioration as the stroma becomes generally cloudy, which could be treated with artificial tear drops, phototherapeutic keratectomy or keratoplasty.

关 键 词：角膜营养不良 角膜混浊 诊断 

分 类 号：R772.2[医药卫生—眼科]