胆道成形术在恶性梗阻性黄疸治疗中的应用价值  

作　　者：茹利新[1] 纪鹏天[1] 许建伟[1] 郑少俊[1] 张海兵[1] 

机构地区：[1]浙江省湖州市中心医院介入放疗科,313000

出　　处：《浙江临床医学》2012年第3期260-262,共3页Zhejiang Clinical Medical Journal

基　　金：浙江省卫生厅资助（2011KYB118）;湖州市科技局资助（2011YS17）

摘　　要：目的 探讨胆道成形术（经皮胆道引流及支架置入）治疗恶性梗阻性黄疸的临床疗效及应用价值.方法 在DSA下对80例梗阻性黄疸患者行经皮肝胆管穿刺置管引流以及胆道内支架置入,观察临床症状和黄疸的改善情况.结果 80例患者穿刺置管引流术均置管成功,其中60例单支架置入,20例双支架置入.术前血清总胆红素（200.67±48）μmol/L,术后1周、2周及3周血清总胆红素分别下降到（140.2 ± 42.8）μmol/L、（90.3±26.5）μmol/L及（60.6±36.5）μmol/L.其中32例患者临床症状改善后行化疗以及放射治疗.结论 胆道成形术可明显改善恶性胆道梗阻的临床症状,提高患者生活质量,为进一步治疗创造条件.Objective To explore the clinical therapeutic effect of bile tract plasty （pereutaneous transbepatic biliary drainage, PTCD） for malignant obstructive jaundice. Methods 80 patients of for malignant obstructive jaundice had PTCD and biliary stent placement. The clinical effects and the improvement of jaundice were observed. Results The procedure was performed successfully in all the 80 patients, among them,60 had one single stent placement and the other 20 had double stents placement. The preoperative serum total bili rubin （ STB ） was （ 200.67 ± 48 ） μmol/L, while it drop to （ 140.2 ± 42.8 ） μmol/L, （ 90.3 ± 26.5 ） μmol/ L 及（60.6 ±36.5 ） μmol/L one week,two weeks and three weeks postoperatively respectively. 32 patients also had chemotherapy and radiotherapy after their symptom got released. Conclusions The bile tract plasty can significantly release the clinical symptoms and improve the life quality for patients with malignant obstructive jaundice, which provides chances for further treatment.

关 键 词：内支架 胆道引流 恶性梗阻性黄疸 

分 类 号：R735.8[医药卫生—肿瘤]