认知行为疗法对首发女性偏执型精神分裂症康复期抑郁情绪疗效观察  

Control study of the effect of cognitive behavioral therapy combined with on the depression syndromes patients who had been in the recovery status of paranoid schizophrenia

作　　者：李志文[1] 和西波[1] 陈玉辉[1] 

机构地区：[1]天津市安宁医院,天津300300

出　　处：《中国民康医学》2012年第5期518-520,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:观察认知行为疗法对首发偏执型精神分裂症康复期患者抑郁情绪的疗效。方法:选取首发偏执型精神分裂症康复期患者100例,随机分为研究组与对照组,研究组在抗精神病药物治疗的基础上给予连续28天每天1个小时的认知行为疗法;对照组只给予原有药物治疗;在研究结束后进行心理治疗,以符合伦理学原则。在治疗前,治疗后以及治疗后12周时进行HAMD量表评分观察焦虑抑郁疗效变化。结果:研究组脱落15例,对照组脱落10例,研究组35例患者治疗后HAMD量表总分[(8.00±1.19)分,(5.05±0.28)分,t=13.430,P<0.001]评分显著低于治疗前,差异具有统计学意义。与对照组相比,治疗后研究组HAMD量表总分[(5.05±0.28)分,(4.04±0.36)分,t=-4.375,P<0.001]低于对照组,差异具有统计学意义。12周随访研究组HAMD量表总分[(8.00±1.19)分,(4.60±0.42)分,t=5.760,P<0.001]。结论:认知行为治疗有助于改善康复期偏执型精神分症患者的抑郁情绪,在12周随访时疗效依然存在。Objective：To explore the influence of clinical symptoms and applicability of Cognitive Behavioral Therapy（CBT） a- mong convalescent schizophrenic patients. Methods： Applying CBT Therapy, 100 convalescent paranoid schizophrenic patients with convalescent clinical state were consecutively recruited. All the patients were randomly divided into CBT group and control group and were pretreated with antipsychotic agent therapy, 35 patientss in CBT group and 40 patients in control group entered the result analysis, 10 lost. In CBT group, the patients received CBT Therapy for successive 28 days. In control group, the patients only received antipsychotic agent therapy. Pre - and post - treatment HAMD, were administered to all subjects. Results： After treatment, in the study group ,HAMD scales [ （8.00 ±1.19） 分, （ 5.05 ±0.28）分, t = 13. 430, P 〈0. 001 ]. The difference was statistically significant. HAMD study group after treatment, total scores [ （5.05 ± 0.28 ）分, （4.04 ±0.36）分, t = - 4. 375, P 〈 0. 001] score significantly lower than the control group. After twelve weeks follow - up study, in the study group, HAMD total scores [ （ 8.00 ±1.19） 分], （4.60 ± 0.42） 分, t = 5. 760, P 〈 0. 001 ] significantly lower than before treatment, the difference was statistically significant . Conclusions ： CBT can possibly improve part depression symptoms of patients with convalescent schizophrenia to a certain extent.

关 键 词：认知行为治疗 偏执型精神分裂症 康复期 抑郁情绪 疗效 

分 类 号：R749.3[医药卫生—神经病学与精神病学]