均匀试验设计法优选产妇康颗粒提取工艺  

Optimization of Extraction Technology for Chanfukang Granule by Uniform Test Design

作　　者：贾永艳[1] 周红敏[1] 贾永[1] 魏超娟[1] 李翠萍[1] 

机构地区：[1]河南中医学院,郑州450008

出　　处：《中国实验方剂学杂志》2012年第7期32-34,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：郑州市科技攻关项目(064SGDS33221-3)

摘　　要：目的:优选产妇康颗粒提取工艺。方法:高效液相法测定提取液中阿魏酸的含量,结合正丁醇浸出物含量,采用均匀实验设计优选产妇康颗粒提取工艺。结果:最佳提取工艺为加8倍量水,浸泡1 h,提取3次,每次1 h。结论:优化后的工艺合理、稳定、可行,适于产妇康颗粒中当归、炮姜等药味的提取。Objective：To optimize extraction technology of Chanfukang granule.Method： The content of ferulic acid was determined by HPLC,combined with the content of N-butanol extract,uniform experiment was used to optimize extraction technology of Chanfukang granule.Result：Optimum extraction process was：soaked 1 h with 8 times the amount of water,extracted 3 times for 1 h each time.Conclusion：Optimized technology of Chanfukang granule was reasonable,stable and feasible,it was suitable for extraction of Angelica sinensis,Zingiber officinale and so on from Chanfukang granule.

关 键 词：产妇康颗粒 阿魏酸 提取工艺 均匀实验设计 

分 类 号：R283.6[医药卫生—中药学]