碱性离子液体的合成及其在Baylis-Hillman反应中的应用  

Study on the Synthesis of Alkaline Ionic Liquids and Application for Baylis-Hillman Reaction

作　　者：易封萍[1] 张旋[1] 孙海洋[1] 陈世洪[2] 

机构地区：[1]上海应用技术学院香料香精技术与工程学院,上海201418 [2]江西环境工程职业学院环境工程系,赣州341000

出　　处：《化学学报》2012年第6期741-746,共6页Acta Chimica Sinica

基　　金：上海市教委重点科研创新项目(No.11ZZ180);上海市科委地方院校能力建设项目(No.11520502600)资助项目~~

摘　　要：采用正交实验优化合成了碱性离子液体氢氧化1-丁基-4-二甲氨基吡啶盐,以其为反应溶剂,在催化剂DABCO(1,4-二氮杂二环[2.2.2]辛烷)作用下进行了芳香醛与丙烯酸甲酯的Baylis-Hillman反应研究.实验结果表明,在该离子液体的存在下,芳香醛与丙烯酸甲酯以较快的反应速度和较高产率生成目标化合物.在此基础上,进一步研究了水-离子液体复合体系对Baylis-Hillman反应的影响,取得了更快的速率及更高的产率.The synthetic methods of alkaline ionic liquid hydroxide 1-butyl-4-dimethyl aminopyridine were optimized by using orthogonal experimental. By using triethylene diamine （DABCO） as catalyst and alkaline ionic liquid as solvent, aromatic aldehydes with methyl acrylate＇s BaylisHillman reaction was stud ied. Experimental results showed that fast reaction rate and high yield were obtained in the presence of the alkaline ionic liquid. On this basis, BaylisHillman reaction under the influence of waterionic liquid com posite system was further studied, and obtained better result.

关 键 词：碱性离子液体 芳香醛 丙烯酸甲酯 BAYLIS-HILLMAN反应 水 

分 类 号：O626.32[理学—有机化学]