三联疗法治疗前部缺血性视神经病变的临床观察  

作　　者：王锋[1] 

机构地区：[1]山东泰安市中医医院眼科,271000

出　　处：《中国社区医师（医学专业）》2012年第9期172-173,共2页

摘　　要：目的:观察脑蛋白水解物、银杏达莫、复方樟柳碱治疗前部缺血性视神经病变(AION)的疗效。方法:临床确诊的AION患者70例(70只眼),其中35例(35只眼)接受三联疗法治疗(治疗组);另外35例(35只眼)接受常规治疗(对照组)。应用溶栓抗凝剂、血管扩张剂静滴治疗,1次/日;糖皮质激素、654-2球后或球旁注射,1～3次/周。均以20天为1个疗程。两组用药后每天观察视力、眼底变化,治疗前有视野检查者复查视野。结果:治疗组视力提高程度明显优于对照组,两组比较,差异有统计学意义(t=2.86,P<0.01);治疗组中,32只眼(91.43%)治疗有效;3只眼(8.57%)无变化。对照组中,27只眼(77.14%)治疗有效;8只眼(22.86%)无变化。两组治疗有效率比较,差异有统计学意义(X2=19.61,P<0.01)。结论:三联疗法治疗AION有效。Objective:To observe the efficacy of triple therapy(Brain hydrolyzate,Yinxingdamo and Compound anisodine) on AION.Methods:In 70 patients(70 eyes) who were diagnosed as with AION,35 patients(35 eyes) were treated with triple therapy(treatment group),and the other 35 patients(35 eyes) were treated with Conventional treatment(control group),including thrombolytic coagulan and vasodilator(once per day);gluco-corticosteroid and 654-2(every week for 1～3 times).two groups have the same period of treatment of 15 days.The changes of visual acuity and ocular fundus of the patients after injection were recorded,and the visual field was counterchecked in the patients who had been examined before the treatment.Results:The visual acuity was better in treatment group than which incontrol group with a significant difference(t=2.86,P<0.01);In treatment group,the therapy was effective to 32 eyes(91.43%);and was invalid to other 3 eyes(8.57%).In control group,the therapy was effective to 27 eyes(77.14%);and was invalid to other 8 eyes(22.86%).There was a significant difference between the two groups(X2=19.61,P<0.01).Conclusions:triple therapy is efficacious in treatment of AION.

关 键 词：前部缺血性视神经病变 脑蛋白水解物 银杏达莫 复方樟柳碱 

分 类 号：R774.6[医药卫生—眼科]