卡培他滨联合放疗对胃癌疗效的影响  

Effect of capecitabine combined with radiotherapy on stomach cancer

作　　者：冯连杰[1] 张庆富[1] 何志杰[1] 申静[1] 魏涛[1] 

机构地区：[1]河南省安阳市肿瘤医院放疗三科,455000

出　　处：《中国实用医刊》2012年第7期3-4,共2页Chinese Journal of Practical Medicine

摘　　要：目的探讨卡培他滨联合放疗治疗胃癌的临床疗效。方法将2008年至2010年收入安阳市肿瘤医院的不能进行手术治疗的62例胃癌患者进行随机分组，卡培他滨组31例，只单纯使用卡培他滨化疗；卡培他滨联合放疗组31例，在使用卡培他滨的同时联合放疗，观察两组治疗后的疗效及并发症。结果联合组有效率为90．3％，不良反应发生率为48．3％；单纯卡培他滨组有效率为67．7％，不良反应发生率为51．6％，两组患者有效率比较差异有统计学意义（P〈0．05），不良反应发生率比较差异无统计学意义。结论卡培他滨联合放疗共同治疗胃癌疗效较好，可作为胃癌患者的一个选择。Objective To investigate the effect of capecitabine combined with radiotherapy on stomach cancer. Methods Sixty-two gastric cancer patients could not underwent surgery from 2008 to 2010 were randomly divided into two groups. Thirty-one cases in capecitabine group were only given capecit- abine chemotherapy; 31 cases in capecitabine combined with radiotherapy group were given capecitabine com- bined with radiotherapy at the same time. The effects and complications were observed. Results The ef- fective rate in capecitabine combined with radiotherapy group was 90.3%, incidence of side effects was 48.3% ; the effective rate in capecitabine group was 67.7% , incidence of side effects was 51.6% ;the difference in effective rates was significant （P 〈 0. 05 ）, and the difference in rates of side effects was not significant between the two groups. Conclusions Capecitabin combined with radiotherapy has better effect in the treatment of stomach cancer, and should be cheosed for patients with stomach cancer.

关 键 词：卡培他滨 放疗 胃癌 疗效 

分 类 号：R735.2[医药卫生—肿瘤]