早期乳腺癌患者行改良根治手术与保乳术的疗效观察  

Comparison of breast-conserving surgery and modified radical mastectomy in patients with early stage breast cancer

作　　者：夏冬[1] 李显蓉[1] 姚晖[1] 

机构地区：[1]泸州医学院附属医院普外科,四川泸州646000

出　　处：《实用肿瘤杂志》2012年第2期133-135,共3页Journal of Practical Oncology

摘　　要：目的分析早期乳腺癌患者分别进行改良根治手术和保乳手术的临床效果。方法 105例早期乳腺癌患者,在知情同意下,按患者及其家属意愿分为保乳组(53例)和改良根治组(52例)。保乳组采用保乳手术治疗,改良根治组采用改良根治手术。结果两组患者2年生存率和复发率比较,差异无统计学意义(P>0.05);保乳组生存质量评分均明显高于改良根治组,差异有统计学意义(均为P<0.05)。结论保乳手术与改良根治手术对患者的生存率、复发率差异无统计学意义,但是保乳手术大大提高了患者的生存质量。Objective To compare the clinical outcomes of breast-conserving surgery and modified radical mastectomy in breast cancer patients.Methods One hundred and five patients with early stage breast cancer were treated with breast conservative surgery（53 cases）or modified radical mastectomy（52 cases）.The clinical outcomes were compared between two groups.Results There were no significant differences in 2-year survival rate and recurrence rate between two group（P0.05）.The score of quality of life for patients with breast-conservative surgery was higher than that for patients with modified radical mastectomy（P0.05）.Conclusion Breast-conserving surgery has the same survival rate and recurrence rate as modified mastectomy for patients with early stage breast cancer,but the patients have better quality of life.

关 键 词：乳腺肿瘤/外科学 乳房切除术 区段 乳房切除术 改良根治性 随访研究 治疗结果 

分 类 号：R737.9[医药卫生—肿瘤] R730.56[医药卫生—临床医学]