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机构地区:[1]中国医学科学院中国协和医科大学肿瘤医院妇瘤科,北京100021 [2]山东省肿瘤防治研究院妇科
出 处:《中华妇产科杂志》2000年第5期270-272,共3页Chinese Journal of Obstetrics and Gynecology
摘 要:目的 研究不同治疗方法对Ⅰ、Ⅱ期子宫内膜癌治疗后复发、转移及并发症的影响。方法 根据不同治疗方法将 2 0 5例Ⅰ、Ⅱ期子宫内膜癌患者分为手术组、术前腔内全量放射治疗 (放疗 )组、术前腔内非全量放疗组和单纯放疗组 4组 ,对其治疗后复发、转移及并发症进行分析、比较。结果手术组、术前腔内全量放疗组、术前腔内非全量放疗组及单纯放疗组的总复发转移率分别为 19.8%、8.1%、2 2 .2 %、34 .6 % ,其中阴道残断复发率分别为 6 .2 %、1.6 %、11.1%、11.5 % ;放疗并发症中 ,放射性直肠炎、膀胱炎的发生率 ,术前腔内全量放疗组均为 3.2 % ,术前腔内非全量放疗组分别为 2 .8%、0 .0 % ,单纯放疗组分别为 0 .0 %、3.8%。结论 术前腔内全量放疗组的复发转移率最低 ,而且放疗后并发症发生率也低 ,是治疗Ⅰ、Ⅱ期子宫内膜癌较为理想的方法。Objective To make an approach to the relationship between recurrence, metastasis and complication of stage Ⅰ and Ⅱ endometrial carcinoma treated by 4 different therapeutic modalities. Methods To compare the rates of recurrence, metastasis and complication in 4 treatment groups (surgery, full dose preoperative intracavitary irradiation, non full dose preoperative intracavitary irradiation and radiation alone). Results Recurrence and metastasis in surgery, full dose preoperative intracavitary irradiation, non full dose preoperative intracavitary and radiotherapy alone groups were 19.8%, 8.1%, 22.2% and 34.6%, respectively. The recurrent rates of vaginal stump were 6.2%, 1.6%, 11.1% and 11.5%, respectively. The rates of proctitis and cystitis in full dose preoperative intracavitary irradiation group were 3.2% and 3.2%, 2.8 and 0.0% in non full dose preoperative intracavitay irradiation group, and 0.0% and 3.8% in radiotherapy alone group. Conclusions The rates of recurrence and metastasis in full dose preoperative intracavitary irradiation group were the lowest compared with other groups and incidence of complication was also low. This therapeutic method is the optimal choice for the treatment of endometrial carcinoma with stage Ⅰ and Ⅱ.
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