基于B样条的弹性配准在放疗CBCT与CT图像配准中的应用研究  

Cone-beam CT and CT Image Non-rigid Registration Using B Spline

作　　者：庞皓文[1] 孙小扬[1] 杨波[1] 罗惠群[1] 吴虹[1] 吴敬波[1] 

机构地区：[1]泸州医学院附属医院肿瘤科,四川泸州646000

出　　处：《医疗卫生装备》2012年第3期116-117,共2页Chinese Medical Equipment Journal

摘　　要：目的:应用B样条弹性模型研究肿瘤患者放疗中锥形束CT图像与CT图像之间的弹性配准。方法:利用B样条自由弹性模型,以灰度差平方和为相似性测度函数,通过基于多分辨率的B样条弹性配准方法对锥形束CT图像与CT图像进行配准。结果:通过处理后的锥形束CT与CT图像虽然成像算法不同,但都得到较为理想的弹性配准实验结果。结论:基于B样条锥形束CT与CT图像弹性配准能较好地建模放疗前与放疗期间肿瘤区域的形变,为临床分析肿瘤的变化提供支持。ObjectiTe To investigate cone-beam CT（CBCT） and CT image non-rigid registration using the B spline.Methods Using B-spline free-form deformations model and SSD as a similarity measure function,the registrations of CBCT and CT images were done using B spline non-rigid registration method based on multi-resolution.Results Although the imaging algorithm between CBCT and CT was different,the results were more satisfactory.Conclusion The non-rigid registration of CBCT and CT images using B spline can model the deformation of tumor region before and during the radiotherapy,which provides a support for the clinical analysis of changes in the tumor.

关 键 词：B样条 弹性配准 自由形变模型 锥形束CT 

分 类 号：TP391.41[自动化与计算机技术—计算机应用技术]