某地区老年健康者和脑梗死患者不同季节血浆同型半胱氨酸水平比较  

Seasonal variation of homocysteine level in healthy elderly volunteers and elderly patients with cerebral infarction in certain area

作　　者：武爱敏[1] 辛晓敏[1] 程峰[2] 金英玉[1] 王丽艳[1] 

机构地区：[1]哈尔滨医科大学附属第一医院检验科,哈尔滨150001 [2]黑龙江省绥化市人民医院检验科,152000

出　　处：《国际检验医学杂志》2012年第6期713-714,共2页International Journal of Laboratory Medicine

摘　　要：目的了解该地区老年健康者和脑梗死患者血浆同型半胱氨酸(Hcy)水平的季节变化。方法采用循环酶法对1105例健康老年者和614例脑梗死患者四季血浆Hcy水平进行检测。结果健康者血浆Hcy水平夏季最低,冬季最高,春季和秋季差异无统计学意义(P>0.05),其他季节差异有统计学意义(P<0.05);不同季节脑梗死患者血浆Hcy水平均高于健康者(P<0.05);不同季节脑梗死患者血浆Hcy水平差异无统计学意义(P>0.05)。结论健康者和脑梗死患者血浆Hcy水平存在不同的季节变化规律;健康者血浆Hcy水平随季节变化而变化,脑梗死患者血浆Hcy水平不随季节变化而变化。Objective To investigate the seasonal variation of plasma homocysteine（Hcy） level in healthy elderly volunteers and elderly patients with cerebral infarction（CI） in certain area.Methods Plasma Hcy level of 1 105 healthy elderly volunteers and 614 elderly patients with CI were measured by enzymatic cycling method in different seasons.Results Plasma Hcy level in healthy elderly volunteers were at lowest in summer and highest in winter.There were no seasonal differences of plasma Hcy level between spring and autumn（P0.05）,but seasonal difference could be demonstrated between other seasons（P0.05）.Plasma Hcy level in elderly patients with CI were higher than healthy volunteers in every season and there were no seasonal differences（P0.05）.Conclusion There might be different regularity about seasonal variation of plasma Hcy level in healthy elderly volunteers and elderly patients with CI.Plasma Hcy level in healthy elderly volunteers could vary with the change of seasons,but there were no seasonal variations in elderly patients with CI.

关 键 词：脑梗死 同型半胱氨酸 季节 老年人 

分 类 号：R743.33[医药卫生—神经病学与精神病学]