瑞香狼毒中2,6,10,15,19,23-六甲基-2,6,10,14,18,22-二十四碳六烯的分离鉴定及其生物活性研究  

Isolation and Identification of 2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene from Stellera Chamaejasme and Research on Its Bioactivity

作　　者：唐孝荣[1] 王玲[1] 

机构地区：[1]西华大学物理与化学学院,四川成都610039

出　　处：《西华大学学报（自然科学版）》2012年第2期77-80,共4页Journal of Xihua University:Natural Science Edition

基　　金：四川省教育厅重点项目(09ZA113);西华大学重点科研基金(Z0913302);西华大学有机化学重点学科;西华大学校级精品课程物理化学(xjjpkc0915)

摘　　要：用氯仿对瑞香狼毒根粉进行提取后,再用硅胶柱对粗提物进行多次分离纯化,最后得到了一个纯化合物,结构鉴定确定其为2,6,10,15,19,23-六甲基-2,6,10,14,18,22-二十四碳六烯(角鲨烯)。以蚕豆蚜和粘虫为靶标对其进行了生物活性测定,结果表明:它对这2种害虫都有较好的杀虫活性,24 h半致死浓度(LC50)分别为18.0,12.7 mg.L-1。The root powder of Stellera chamaejasme was extracted with chloroform.The crude extract obtained was chromatographed with silica gel columns several times.One pure compound was obtained.It was identified as 2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene（squalene）.Its insecticidal activity against Aphis craccivora and Leucania separata was determined.The results showed that it had good insecticidal activity against them.Its median lethal concentration（LC50）（24 h after treatment） was 18.0 mg·L-1 and 12.7 mg·L-1,respectively.

关 键 词：瑞香狼毒 角鲨烯 蚕豆蚜 粘虫 生物活性 

分 类 号：S482[农业科学—农药学]