氟化钠抗碳酸饮料酸蚀乳牙釉质作用的研究  

Protective effects of sodium fluoride on primary tooth enamel erosion caused by carbonated beverages

作　　者：王雪芹[1,2] 王鹏[1,2] 姜广水[1] 

机构地区：[1]山东大学口腔医学院,山东济南250012 [2]山东省烟台市口腔医院,山东烟台264001

出　　处：《口腔生物医学》2012年第1期33-35,40,共4页Oral Biomedicine

摘　　要：目的:探讨氟化钠抗碳酸饮料对乳牙釉质酸蚀的效果。方法:用人下颌乳切牙制备72个釉质块,将其随机平均分为3组:对照组釉质块不作涂氟处理,实验组两组釉质块分别涂0.6%和1.23%浓度氟化钠;各组再按浸泡在碳酸饮料中的时间不同分成30 min和50 min两个亚组。将各组釉质块分别浸泡于碳酸饮料中30 min或50 min,取出后用去离子水冲洗,将实验组重新涂氟,然后再将釉质块浸泡在碳酸饮料中,如此循环直至12 h。用扫描电镜观察乳牙釉质表面形态改变,显微硬度计测定釉质表面硬度值(surface micro-hardness,SMH)变化,评估氟化钠保护乳牙釉质抗碳酸饮料酸蚀的效果。结果:与对照组比较,经两种浓度氟化钠处理过的乳牙釉质能不同程度地抵抗碳酸饮料的酸蚀作用,SMH值较高(P<0.05);随着碳酸饮料浸泡时间的延长,氟化钠保护乳牙釉质抗酸蚀的能力下降;较高浓度的氟化钠的保护效果更好,差异有统计学意义(P<0.05)。结论:氟化钠能够增强乳牙釉质抗碳酸饮料酸蚀能力。Objective：To investigate the protection of sodium fluoride on the enamel of deciduous tooth from erosion by carbonated beverages.Methods：Seventy-two enamel blocks were made from human deciduous teeth as samples for the study,and were randomly divided equally into three groups,and each group was divided further into two subgroups according to their immersion duration in carbonated beverages（30min or 50min）.Samples in experimental group A and B were respectively treated with 0.6% and 1.23% sodium fluoride,while these in control group were without abovementioned managements.Samples of two subgroups were immersed in carbonated beverages（Coca-Cola） for 30 min and 50 min,respectively.After that,the samples were washed with distilled water.And then,the samples were re-immersed in Coca-Cola with same format after the samples in experimental groups were re-treated with the sodium fluoride.Such immersion-wash circling was kept on for 12 h.To assess the resistance,reinforced by sodium fluoride,of enamel of deciduous teeth to acid erosion caused by Coca-Cola,the structural changes on enamel surface were observed with scanning electron microscope.The hardness of enamel was measured by the surface micro-hardness（SMH）.Results：Compared to the control,enamel treated with sodium fluorides was more resistant to acid erosion（P0.05）,with the protective effects being commensurate with concentration of fluoride in the foams（P0.05）.As the immersion time in Coca-Cola prolonged,the protection of the foam weakened accordingly.Conclusions：Sodium fluoride could enhance enamel′s resistance to acid erosion caused by carbonated beverages.

关 键 词：氟化钠 碳酸饮料 釉质酸蚀 乳牙 

分 类 号：R780.1[医药卫生—口腔医学]