无功能型垂体腺癌2例报告并文献复习  

Non-functioning pituitary carcinoma: report of two cases and review of literature

作　　者：宋烨[1] 漆松涛[1] 彭玉平[1] 龙浩[1] 刘华[1] 

机构地区：[1]南方医科大学南方医院神经外科,广东广州510515

出　　处：《南方医科大学学报》2012年第4期539-543,共5页Journal of Southern Medical University

基　　金：广东省自然科学基金(S2011010005643)

摘　　要：目的探讨无功能型垂体腺癌的临床特点、诊断及治疗策略。方法通过2例无功能型垂体腺瘤的诊断与治疗经过,并结合现有文献对本病进行探讨。结果 2例无功能型垂体腺瘤患者经过外科手术、立体定向放射治疗后肿瘤仍旧复发,分别在发病后3个月和5个月死亡。结论垂体腺癌非常罕见,需要结合临床表现、影像学、细胞学、免疫组化等进行诊断,在进行常规治疗的同时需要寻找更为有效的办法控制肿瘤进展。Pituitary carcinoma is extremely rare.We report two cases of non-functioning pituitary carcinoma treated in our hospital.The two female patients,aged 39 and 40 years,were diagnosed by CT and MRI and postoperative pathological examination.The tumor was surgically resected followed by stereotactic radiotherapy.Despite of the treatments,both of the patients showed tumor recurrence and died at 1 and 2 months after discharge.The diagnosis of this disease relies on a combined evaluation of the clinical,radiological,cytological,immunohistochemical features.Due to the highly malignant nature and poor prognosis of this disease,early surgical intervention and systemic evaluation of the patients＇ condition are imperative.Currently more effective therapeutic approaches are needed to control the tumor progression.

关 键 词：垂体腺癌 无功能型 病例报道 

分 类 号：R736.4[医药卫生—肿瘤]