甲状腺癌合并甲状腺疾病的统计分析  

Statistic analysis of thyroid carcinoma coexistent with thyroid diseases

作　　者：柴红[1] 陈泽泉[2] 余永利[2] 

机构地区：[1]苏州大学,江苏省在读研究生215325 [2]上海交通大学附属第六人民医院核医学科

出　　处：《中华临床医师杂志（电子版）》2012年第6期50-53,共4页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：目的探讨甲状腺癌合并甲状腺疾病的变化趋势。方法回顾性统计分析2003年1月至2010年12月我科131I治疗的经病理证实的1744例甲状腺癌病例资料。初次手术病理资料2000年之前的为一组,2000年以后的病理资料,每2年合并为一组,用卡方或卡方趋势检验分析甲状腺癌合并结节性甲状腺肿(简称结甲)、桥本甲状腺炎(HT)、甲状腺腺瘤(TA)的变化趋势。结果 2007～2008年、2009～2010年的甲状腺癌合并结甲的百分比与2000年以前相比差异有统计学意义(P均<0.01),并且2005～2006年、2007～2008年、2009～2010年的甲状腺癌合并HT的百分比与2000年之前相比差异也有统计学意义(P均<0.01)。甲状腺癌合并TA以2005～2006年为界,在此之前逐年递增,在此之后与之相反。甲状腺癌的男女发病比例在25岁之前达到高峰,女性为男性的3倍,但是随着年龄增加逐渐趋于平衡。结论近几年来甲状腺癌合并结甲、合并HT较前明显增高,而合并TA有下降趋势。Objective To investigate the change of the percentage of thyroid carcinoma（TC）complicated with thyroid diseases.Methods 1744 cases of TC which had confirmed pathologically after surgery,and received iodine therapy in our department during recent 8 years were retrospectively analyzed.The cases of before 2000 were one group,and after that year the cases were divided into five groups and every group includes two years,which checked the change of the percentage with chi square or chi square for trend analysis.Results Compared with 2000 group,both the percentage of TC with nodular goiter in 2007-2008,2009-2010（P0.01）and that with Hashimoto＇s thyroiditis（HT）in 2005-2006,2007-2008 and 2009-2010（P0.01）greatly increased.The incidence of TC with thyroid adenoma（TA）was raised up before 2005-2006,but it began to descend after those years.TC was three times more frequent in women than in men before the age of 25,but the sex ratio was dropped with the increasement of age.Conclusions Both the coexistent rate of TC with nodular goiter and that with HT greatly increase recently,while that with TA tends to decrease.

关 键 词：甲状腺肿瘤 甲状腺肿 结节性 桥本病 甲状腺腺瘤 

分 类 号：R736.1[医药卫生—肿瘤] R581[医药卫生—临床医学]