V—EEG与SPECT联合应用在顽固性癫痫术前致痫灶定位中的价值  

Localization of the epileptogenic focus in patients with refractory epilepsy judged by V-EEG and SPECT

作　　者：王俊伟[1] 吴南[1] 兰川[1] 黄定德[2] 吴国材[1] 冯华[1] 

机构地区：[1]第三军医大学西南医院神经外科,全军神经系统疾病微创诊治专科中心,重庆400038 [2]第三军医大学西南医院核医学科,重庆400038

出　　处：《癫痫与神经电生理学杂志》2012年第2期75-77,共3页Journal of Epileptology and Electroneurophysiology(China)

摘　　要：目的：探讨视频脑电图（V—EEG）与单光子发射计算机断层扫描（SPECT）联合应用在顽固性癫痫术前致痂灶定位中的价值。方法：对103例顽固性癫痫患者，在MRI扫描的基础上，术前行V—EEG和SPECT检查，联合定位致痫灶，通过术中皮层脑电图（ECoG）检查验证致痫灶定位的准确性。结果：103例患者发作间期V—EEG检查均有异常，85例患者检查过程中有癫痫发作1～3次。SPECT检查异常95例，其中表现为放射性核素稀疏区86例，放射性核素浓聚区9例。术前两者联合定位致痫灶91例，与术中ECoG所确定的致痫灶部位一致者85例，符合率为93．4％。结论：术前V-EEG与SPECT的联合应用可以较准确地定位顽固性癫痫的致痫灶，该法对于MRI无异常的癫痫患者之术前致痫灶定位尤其具有重要意义。Objective：To explove the value of VEEG and SPECT in localizing epileptogenie focus in patients with refractory epilepsy. Methods： MRI,VEEG and SPECT were performed in 103 patients with refractory epilepsy. The epileptogenic focus was judged by the results of VEEG and SPECT. The focus was confirmed with eleetrocorticography. Results： VEEG abnormality was found in all patients, SPECT abnormality in 95 of 103 patients. The 85/91 patients were identical with the epileptogenic focus judged by ECoG. Conclusion： It is a useful way ,to localize the epileptogenic loci in patients with refractory epilepsy judgen by VEEG and SPECT before operation, especially in patients with normal MRI.

关 键 词：视频脑电图(V—EEG) 单光子发射计算机断层扫描(SPECT) 致痫灶 

分 类 号：R741.044[医药卫生—神经病学与精神病学] R742.1[医药卫生—临床医学]