乌鲁木齐市公务员非酒精性脂肪肝调查  

Analysis of the prevalence of Nonalcoholic Fatty Liver Disease in Uygur Civil Servants in Urumqi

作　　者：张泽高[1] 薛黎[2] 张跃新[1] 肖琳[1] 

机构地区：[1]新疆医科大学第一附属医院感染科,新疆乌鲁木齐830054 [2]新疆医科大学第一附属检验科

出　　处：《现代预防医学》2012年第8期1955-1957,共3页Modern Preventive Medicine

基　　金：新疆自治区重点学科(内科学)经费(传染病学学科建设专项基金)(2009-区教委-01)

摘　　要：目的了解乌鲁木齐市汉族和维吾尔族(简称维族)公务员非酒精性脂肪肝(NAFLD)的患病率及其与代谢综合征(MS)各组分的关系。方法对乌鲁木齐市2009年8月～2010年8月期间公务员体检资料进行单因素、Logistic回归、分层卡方分析两民族NAFLD与MS各组分,体检内容包括血压、体重指数、腹部B超、空腹血糖、胆固醇(CHOL)、甘油三酯(TG)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、肝功能(ALT、AST、GGT)。结果 NAFLD总的患病率为34.09%,汉族和维族分别为33.7%和40.58%,差异有统计学意义(P﹤0.05);两民族MS各组分中高血压、2型糖尿病、血脂异常患病率差异无统计学意义,向心性肥胖患病率差异有统计学意义;NAFLD与MS各组分相关性差异均有统计学意义(P﹤0.05);两民族按体重分层后,脂肪肝检出率差异无统计学意义。结论 MS各组分均与NAFLD相关;乌鲁木齐市汉族和维族公务员脂肪肝的患病率存在差异;这种差异是由两民族的肥胖人口比例不同引起的。OBJECTIVE To determine the prevalence of Nonalcoholic Fatty Liver Disease（NAFLD）in Han、Uygur Civil Servants in Urumqi city,and to analyze the association among NAFLD and the components of Metabolic Syndrome（MS）.METHODS The physical examination data of Civil Servants from August 2009 and August 2010 in Urumqi were analyzed,the data included blood pressure,body mass index,abdominal ultrasonography exam,serum lipids detection（TC,TG,LDL-C,HDL-C ALT,AST and GGT）and blood glucose.RESULTS The total ratio of NAFLD was 34.09% and 33.7% in Han group,40.58% in Uygur group,there was significant difference（P﹤0.05）;There was no significant difference in the prevalences of the MS＇ components such as hypertension,type 2 diabetes and dyslipidemia between Han group and Uygur group,but the case rate of obesity in Uygur group was higher than in Han group;while the association among NAFLD and the MS＇s components was examined by using Logistic Regression,and the result was positive.The prevalence of NAFLD did not show significant difference between Han group and Uygur group while hierarchically analyzed by body weight.CONCLUSION The components of MS were associated with NAFLD;There was difference on prevalence of fatty liver between the Han and Uygur civil servants in Urumqi.This difference was not caused by the ethnic itself,and may be casued by the obesity of different population.

关 键 词：非酒精性脂肪肝 代谢综合征 公务员 

分 类 号：R575.5[医药卫生—消化系统]