^(13)C-辛酸呼气试验测定肝硬化胃固体排空功能研究  

Measurement of solid gastric emptying by ^(13)C-octanoic acid breath test in patients with cirrhosis

作　　者：泽塔多吉[1,2] 吕洪敏[3] 向慧玲[3] 李凤惠[1] 

机构地区：[1]天津医科大学三中心临床学院消化内科,天津300170 [2]西藏昌都地区人民医院,昌都854000 [3]天津市第三中心医院消化内科,天津300170

出　　处：《天津医科大学学报》2012年第1期86-88,共3页Journal of Tianjin Medical University

摘　　要：目的:观察13C-辛酸呼气试验测定肝硬化患者胃固体排空功能变化特点。方法:选取43例乙肝肝硬化患者测定胃固体食物排空时间并与10例健康对照者的胃固体食物排空时间进行比较,按Child-pugh分级进行A、B、C 3级之间胃固体排空时间的比较。结果:乙肝肝硬化患者GET1/2和Tlag较健康对照组明显延长(P<0.05);乙肝肝硬化组Child-pugh分级A级与健康对照组GET1/2无统计学差异(P>0.05),B级、C级患者GET1/2较健康对照组明显延长(P<0.05)。结论:肝硬化患者存在胃排空延迟,表现为肝功能Child-pugh评分越高胃排空能力越弱;肝硬化患者Child-pugh A级患者与健康正常者比较胃排空无明显延迟。Objective： To observe the changes of gastric emptying functions in patients with cirrhosis with 13 C-octanoic acid breath test.Methods： Select 43 cases of hepatitis B virus（HBV） related liver cirrhosis and 10 healthy controls.The gastric emptying time of solid food was then measured in both groups and the gastric half-emptying time was compared.Results： The GET 1/2 and Tlag of HBV related liver cirrhosis were prolonged significantly than those of healthy control group（P0.05）.There was no significant difference in GET 1/2 of Child-pugh grade A of HBV related cirrhosis and the control group（P0.05）.Compared with control group,the GET 1/2 of Child-pugh grade B and C was prolonged significantly（P0.05）.Conclusion： There is delayed gastric emptying in patients with cirrhosis,which displays the higher of Child-pugh scores,the weaker of gastric emptying ability.There are not delayed significantly in gastric emptying time in Child-pugh class A patients of HBV related cirrhosis compared with control group.

关 键 词：13C-辛酸呼气试验 胃半排空时间 肝硬化 胃肠动力 

分 类 号：R575.2[医药卫生—消化系统]