唐氏综合征产前筛查服务利用情况及影响因素  被引量:17

Influencing factors and utilization status of prenatal screening for Down's syndrome

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作  者:顾而洲[1] 谷茜[1] 韩鹏[2] 田丹 陈英耀[1] 

机构地区:[1]复旦大学公共卫生学院医院管理教研室,上海200032 [2]中日友好医院办公室 [3]上海儿童医学中心质量管理科

出  处:《中华预防医学杂志》2012年第4期307-310,共4页Chinese Journal of Preventive Medicine

基  金:基金项目:“十一五”国家科技支撑计划(2006BA105A01)

摘  要:目的了解产妇对唐氏综合征产前筛查(简称唐氏筛查)服务的利用情况及影响因素。方法2007年10月至2008年12月,采用整群分层抽样的方法,在中国东、中、西部的浙江、湖南、四川,共抽取54个医疗机构的4250名产妇进行调查。采用《分娩产妇对唐氏综合征产前筛查和诊断干预利用及影响因素调查问卷》渊查人口学特征、健康行为等,以住院产妇的病史记录作为判断受访产妇孕期是否利用唐氏筛查的依据。采用X2检验、logistic回归等对数据进行分析。结果调查对象年龄为(26.92±4.60)岁。唐氏筛查总体利用率为40.0%(1696/4237),其中,浙江、湖南、四川分别为48.23%(682/1414)、41.73%(616/1476)、29.55%(398/1347),大专及以上学历者、高中及以下者分别为72.68%(697/959)、30.46%(998/3276),城镇与农村户籍者分别为63.00%(952/1511)、27.11%(732/2700),年龄〈35岁者与≥35岁者分圳为41.40%(1645/3973)、19.32%(51/264),差异均有统计学意义(P值均〈0.05)。有79.14%(1419/1793)的调查对象认为唐氏筛查有必要,获得过医生建议者占79.47%(1506/1895)。听说过唐氏综合征的调查对象中,24.2%(654/2702)的能辨识其主要致病因素,23.0%(621/2702)的不了解任何引发唐氏综合征的影响因素;77.8%(2102/2702)的听说过唐氏筛查,但12.3%(259/2102)的不清楚进行筛查的具体孕周;47.0%(988/2102)的主要是通过医务人员了解到軎氏筛查。logistie回归分析结果显示,生活在浙江(OR:1.62,95%CI:1.26~2.08)、城镇户籍(OR=2.06,95%CI:1.63~2.60)、认为唐氏筛查有必要(OR=5.00,95%CI:3.97~6.29)、产妇年龄〈35岁(OR=3.86,95%CI:2.53~5.89)、获得过医生建议(OR=12.64,95%CObjective To describe the pregnant women's utilization of prenatal screening for Down's syndrome and its influencing factors, Methods From October 2007 to December 2008, 4250 lyingin women in 54 hospitals were surveyed by stratified cluster sampling method in Zhejiang, Hunan and Sichuan, which located in Eastern, Central and Western China, respectively. Demographic characteristics, knowledge and health behaviors were collected by the questionnaire of lying-in women's utilization and influencing factors of prenatal screening for Down's syndrome. Whether to use prenatal screening was determined by the lying-in women's medical history. Chi-square test and logistic regression analysis were used to analyze datas. Results Respondents' age was ( 26. 92 ± 4. 60) years old. The total utilization rate of prenatal screening for Down' s syndrome wa,; 40.0% (1696/4237), and screening utilization rates in Zhejiang, Hunan and Sichuan were 48.23% (682/1414) ,41.73% (616/1476) and 29. 55% (398/1347), respectively. Screening utilization rates of respondents with college degree or above and high school or below were 72.68% (697/9591 and 30. 46% (998/3276) , respectively. Sereenlng utilization rates of urban and rural respondents were 63. 00% (952/1511 )and 27. 11% (732/2700), respectively. Screening utilization rates of respondents under 35 years old and over 35 years oht were 41. 40% ( 1645/3973 ) and 19.32% (51/264). All differences were significant ( all P values 〈 0. 05 ). A total of 79. 14% ( 1419/1793 ) of respondents thought it was necessary to take prenatal screening for Down's syndrome, and 79.47% ( 1506/1895 )of respondents received doctors' suggestions, 24. 2% (654/2702) of respondents who heard of prenatal screening lor Down's syndrome could figure out the main pathogenic factors, while 23.0% (621/2702) didn't know any taetors; 77.8% (2102/2702)of respondents heard of prenatal screening for Down's syndrome, hut 12.3% (259/210

关 键 词:唐氏综合征 遗传筛查 产前筛查 因素分析 统计学 

分 类 号:R714.5[医药卫生—妇产科学]

 

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