恶性实体肿瘤脑膜转移的研究进展  

Research progress on leptomeningeal metastases of solid carcinoma

作　　者：潘振宇(综述)[1] 王爱林(综述)[2] 董丽华(审校)[1] 

机构地区：[1]吉林大学第一医院肿瘤中心,130021 [2]吉林大学第一医院检验科,130021

出　　处：《肿瘤研究与临床》2012年第3期208-210,共3页Cancer Research and Clinic

摘　　要：恶性实体肿瘤脑膜转移发生率约5％～8％，是恶性肿瘤的致死性并发症。其临床表现不。典型，误诊率高，诊断复杂，主要依据脑脊液相关检查及神经影像学检查。尽管采用放、化疗，的多学科综合治疗，但属姑息治疗，疗效仍不理想，患者生存期极短。Leptomeningeal metastasis （LM）, with a high omission rate in diagnosis in approximately 5 %-8 % of all patients, is increasingly recognized as a lethality complication. The diagnosis of LM remains challenges,but commonly can be established by CSF cytology or by definitive neuroimaging. Although a combination of focal radiotherapy, intrathecal chemotherapy, and systemic chemotherapy may be necessary to achieve optimal treatment of patients, but prognosis is unacceptable and therapy remains palliative in most patients.

关 键 词：脑膜 诊断 肿瘤转移 

分 类 号：R730.5[医药卫生—肿瘤]