颈动脉斑块的稳定性与脑梗死程度的临床研究  

Clinical Research of the Stability of Carotid Plaques with Cerebral Infarction Degree

作　　者：李玲玲[1] 潘燕[1] 张桂萍[1] 迪利努尔[1] 高晓丽[1] 

机构地区：[1]新疆医科大学第五附属医院,新疆乌鲁木齐830011

出　　处：《中国医药指南》2012年第9期17-19,共3页Guide of China Medicine

摘　　要：目的观察颈动脉斑块稳定性与脑梗死严重程度的关系。方法 120例首发脑梗死患者,其中男性72例,女性48例;年龄34～86岁,平均年龄61.9岁。诊断标准:脑梗死的诊断采用全国第四届脑血管病学术会议脑血管病诊断标准。颈动脉稳定斑块和不稳定斑块的标准由颈动脉彩色多普勒超声(CDFI)及MSCTA检查确诊。纳入标准:①符合全国第四届脑血管病学术会议脑血管病诊断标准,并经头颅CT或磁共振成像检查证实;②首次发作脑梗死;③病程在48h内;④意识清楚,无智力、语言理解和表达明显障碍。排除标准:①发病后超过48h住院者;②患有感染或自身免疫性疾病者;③伴心、肺、肝、肾功能不全者;④血液病或肿瘤患者。将符合研究标准的分别行颈动脉超声、MSCTA检查,并分为稳定斑块组(68例)和不稳定斑块组(52例),应用美国国立卫生研究院卒中量表(NIH StrokeScale,NIHSS)和Barthel指数量表进行神经功能缺损和日常生活能力评估。结果 MSCTA与CDFI对脑梗死患者颈动脉粥样硬化病变的比较影像学评价一致性为73.10%;不稳定斑块组NIHSS评分明显高于稳定斑块组[(4.45±2.56)分比(2.45±2.63)分,P<0.01];Barthel指数不稳定斑块组明显低于稳定斑块组[(65.35±28.92)比(78.56±24.35),P<0.05]。结论脑梗死伴不稳定斑块患者神经功能缺损较重,日常生活能力较差。Objective Observing the carotid plaques stability and cerebral infarction severity of the relationship.Methods 120 cases of patients with cerebral infarction,starting 72 men cases,female 48 cases;34 to 86 years of age,with an average age of 61.9 years.Diagnosticcriteria： cerebral infarction of the diagnosis of the fourth national cerebrovascular disease academic conference cerebrovascular disease diagnosis standard.Carotid plaques and stable unstable the standard of carotid plaques by color doppler ultrasound（CDFI） and MSCTA tests identified.Inclusion criteria： ①Comply with the fourth national cerebrovascular disease academic conference cerebrovascular disease diagnosis standard,and the head CT or mri（magnetic resonance imaging） check proof;②The first attack cerebral infarction;③In the course of the 48 h inside;④The consciousness,no intelligence,clear language understanding and the expression obvious obstacle.Exclusion criteria： ①The incidence after more than 48 h about;②With infection or autoimmune diseases,those who ③with heart,lung,liver,kidney function is not complete person;④the blood or cancer patients.Will comply with the standard do research respectively carotid ultrasound,MSCTA inspection,and divided into stable plaques group（68 cases） and unstable plaques group（52 cases）,the application of the U.S.national institutes of health Stroke Scale（NIHSS） scores,NIH Stroke Scale and Barthel index Scale for neural function defect and daily living skills assessment.Results MSCTA and CDFI patients with cerebral infarction of carotid atherosclerotic lesions in the imaging evaluation for 73.10% more consistency;Unstable plaques NIHSS scores of significantly higher than stable plaques group [4.45 ＋ /-2.56 points better than 2.45 ＋ /-2.63 points,P 0.01];Barthel index is not stable plaques group was significantly lower than the stable plaques group [65.35 ＋ /-28.92） than 78.56 ＋ /-24.35,P0.05）.Conclusion Cerebral infarction patients with unstable plaques neural funct

关 键 词：脑梗死 颈动脉斑块 稳定性 不稳定性 

分 类 号：R743.3[医药卫生—神经病学与精神病学]